Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study

Sulfotransferases (SULT) catalyze both the bioactivation and detoxification of a wide range of promutagens and procarcinogens. SULT1A1 appears to be an important phenol SULT because of its abundance and distribution in many tissues and wide substrate specificity. The SULT1 A1 gene possesses a G→A po...

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Veröffentlicht in:	Cancer letters 2003-12, Vol.202 (1), p.61-69
Hauptverfasser:	Zheng, Leizhen, Wang, Yunfei, Schabath, Matthew B, Grossman, H.Barton, Wu, Xifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Antineoplastic agents Arylsulfotransferase Biological and medical sciences Bladder cancer Breast cancer Case-Control Studies Colorectal cancer Disease prevention DNA - blood DNA - genetics Enzymes Female Gene Frequency Genes Genotype Genotype & phenotype Health risk assessment Humans Lung cancer Male Medical sciences Middle Aged Molecular epidemiology Patients Pharmacology. Drug treatments Phenols Polymorphism, Genetic Questionnaires Risk Factors Single nucleotide polymorphism Skin cancer Smoking Smoking - adverse effects Studies Sulfotransferases - genetics Sulfotransferases - metabolism SULT1A1 Tumors Urinary Bladder - enzymology Urinary Bladder Neoplasms - enzymology Urinary Bladder Neoplasms - genetics
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