Losing heart: the role of apoptosis in heart disease—a novel therapeutic target?

ABSTRACT Cardiovascular disease is a leading cause of death worldwide. In recent years it has emerged that loss of myocardial cells may be a major pathogenic factor. Cell death can occur in a destructive, uncontrolled manner via necrosis or by a highly regulated programmed cell suicide mechanism ter...

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Veröffentlicht in:	The FASEB journal 2002-02, Vol.16 (2), p.135-146
Hauptverfasser:	Gill, Catherine, Mestril, Ruben, Samali, Afshin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Apoptosis - drug effects Calcineurin - therapeutic use cardiomyopathy Cardiovascular Diseases - drug therapy Cardiovascular Diseases - pathology Caspase Inhibitors cell death Cysteine Proteinase Inhibitors - therapeutic use heat shock proteins Humans ischemia
Online-Zugang:	Volltext
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