Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes

We have cloned a chick homologue of Drosophila dachshund (dac), termed Dach1. Dach1 is the orthologue of mouse and human Dac/Dach (hereafter referred to as Dach1). We show that chick Dach1 is expressed in a variety of sites during embryonic development, including the eye and ear. Previous work has d...

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Veröffentlicht in:	Mechanisms of development 2002-02, Vol.111 (1-2), p.75-87
Hauptverfasser:	Heanue, Tiffany A, Davis, Richard J, Rowitch, David H, Kispert, Andreas, McMahon, Andrew P, Mardon, Graeme, Tabin, Clifford J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Chick Embryo Cloning, Molecular DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drosophila - genetics Drosophila Proteins Ear - abnormalities Ear - embryology Ear - growth & development Eye - embryology Eye Proteins - genetics Eye Proteins - metabolism Female Gene Expression Regulation, Developmental Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Intracellular Signaling Peptides and Proteins Male Mice Mice, Inbred C57BL Mice, Mutant Strains Molecular Sequence Data Nervous System - embryology Nuclear Proteins - genetics Paired Box Transcription Factors PAX2 Transcription Factor PAX6 Transcription Factor Protein Tyrosine Phosphatases Repressor Proteins Sequence Homology, Amino Acid Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - genetics Transcription Factors - metabolism
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