Increasing Local Levels of IGF-I mRNA Expression Using Adenoviral Vectors Does Not Alter Oligodendrocyte Remyelination in the CNS of Aged Rats

IGF-I, a growth factor that contributes to developmental myelination, shows increased levels of expression within experimental models of remyelination. The pattern of IGF-I mRNA expression changes with the rate of remyelination, with peak levels of expression occurring earlier during rapid remyelina...

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