Behavioural pharmacology of polygalasaponins indicates potential antipsychotic efficacy

Polygalasaponins were extracted from a plant ( Polygala tenuifolia Willdenow) that has been prescribed for hundreds of years to treat psychotic illnesses in Korean traditional medicine. Previous in vitro binding studies suggested a potential mechanism for its antipsychotic action, as polygalasaponin...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2002-01, Vol.71 (1), p.191-195
Hauptverfasser:	Chung, In-Won, Moore, Nicholas A., Oh, Won-Keun, O'Neill, Michael F., Ahn, Jong-Seog, Park, Joo-Bae, Kang, Ung Gu, Kim, Yong Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - pharmacology Antipsychotics Behavior, Animal - drug effects Behavior, Animal - physiology Behavioural pharmacology Biological and medical sciences Climbing behaviour Dopamine Dose-Response Relationship, Drug Female General pharmacology Magnoliopsida Male Medical sciences Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy - methods Plant Extracts - pharmacology Plant Roots Polygala Polygalasaponin Rats Receptors, Dopamine - physiology Receptors, Serotonin - physiology Saponins - pharmacology Serotonin
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