Ethanol-stimulated serotonin release in the ventral hippocampus: an absence of rapid tolerance for the alcohol-preferring P rat and insensitivity in the alcohol-nonpreferring NP rat

This study examined the acute effects of intraperitoneal administration of ethanol on the extracellular levels of serotonin (5-HT) in the ventral hippocampus (vHIP) of adult, male alcohol-preferring P and -nonpreferring NP rats. Using in vivo microdialysis coupled with HPLC and electrochemical detec...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2002-01, Vol.71 (1), p.111-117
Hauptverfasser:	Thielen, R.J., Bare, D.J., McBride, W.J., Lumeng, L., Li, T.-K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute ethanol Alcohol Drinking - genetics Alcohol Drinking - metabolism Alcohol-nonpreferring NP rats Alcohol-preferring P rats Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Central Nervous System Depressants - pharmacology Choice Behavior - drug effects Choice Behavior - physiology Dose-Response Relationship, Drug Drug Tolerance - physiology Ethanol - pharmacology Hippocampus - drug effects Hippocampus - metabolism intraperitoneal administration Male Median raphe nucleus Medical sciences Microdialysis Rats Serotonin Serotonin - metabolism Species Specificity Toxicology Ventral hippocampus
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