Role of the "dogbone" effect of balloon-expandable stents: quantitative coronary analysis of DUET and NIR stent implantation introducing a novel indexing system
Stent design and deployment characteristics of balloon-expandable stents may play an important role in determining both early and late outcomes of stenting. The purpose of this study was to compare the percent residual stenosis (RS) of two new-generation stent delivery systems, DUET and NIR, in pati...
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| Veröffentlicht in: | The Journal of invasive cardiology 2002-02, Vol.14 (2), p.59-65 |
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| creator | Hehrlein, Christoph DeVries, Jennifer J Arab, Amina Haller, Scott D Kloostra, Ann Lauer, Michael A Foster, Malcom T Fischell, Tim A |
| description | Stent design and deployment characteristics of balloon-expandable stents may play an important role in determining both early and late outcomes of stenting. The purpose of this study was to compare the percent residual stenosis (RS) of two new-generation stent delivery systems, DUET and NIR, in patients with CAD. From September 1998 1999, a total of 100 consecutive patients with CAD receiving either a DUET (18 or 23 mm length; n = 50) or NIR stent (16 or 25 mm length; n = 50) using a 3.0 or 3.5 mm stent delivery system were compared by quantitative coronary analysis. The ability of each balloon delivery system to fully expand the stent was assessed using a new scoring index entitled the stent delivery balloon expansion ratio (SDBR; %). A high SDBR correlates with the angiographic appearance of a "dogbone" that is sometimes seen during stent deployment. A stent "scalloping" score was developed to quantitatively assess the cobblestone appearance observed angiographically with plaque protrusion after stent implantation. Mean deployment pressures were 14 +/- 2 atm (DUET) and 13 +/- 2 atm (NIR) (p=NS). Extent of elastic recoil was similar (6 +/- 5% for DUET vs. 6 +/- 4% for NIR; (p=NS). "Scalloping" was more pronounced in the DUET stent (score, 0.66 +/- 0.6 for DUET vs. 0.24 +/- 0.4 for NIR; p < 0.001). SDBR and RS were higher with DUET than with NIR stent implantation (SDBR, 15 +/- 5% vs. 12 +/- 5%; RS, 14 +/- 5% vs. 11 +/- 6%; p < 0.01). Multivariate analysis showed that SDBR and stent recoil, but not "scalloping", were associated with increased RS after stent implantation (r = 0.45 and p < 0.001 for "dogbone" effect; r = 0.39 and p < 0.001 for stent recoil).
The second-generation DUET and NIR stents and their respective delivery systems show angiographically different acute performance characteristics. Insufficient deployment of stents visualized by the "dogbone" effect plays a role in the extent of RS after stenting. The introduced angiographic indexes require further validation. |
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The second-generation DUET and NIR stents and their respective delivery systems show angiographically different acute performance characteristics. Insufficient deployment of stents visualized by the "dogbone" effect plays a role in the extent of RS after stenting. The introduced angiographic indexes require further validation.</description><identifier>ISSN: 1042-3931</identifier><identifier>PMID: 11818639</identifier><language>eng</language><publisher>United States</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Blood Vessel Prosthesis Implantation - instrumentation ; Blood Vessel Prosthesis Implantation - methods ; Catheterization - instrumentation ; Coronary Angiography ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - therapy ; Coronary Restenosis - diagnostic imaging ; Coronary Restenosis - etiology ; Equipment Design - methods ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Predictive Value of Tests ; Prospective Studies ; Severity of Illness Index ; Stents ; Treatment Outcome</subject><ispartof>The Journal of invasive cardiology, 2002-02, Vol.14 (2), p.59-65</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11818639$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hehrlein, Christoph</creatorcontrib><creatorcontrib>DeVries, Jennifer J</creatorcontrib><creatorcontrib>Arab, Amina</creatorcontrib><creatorcontrib>Haller, Scott D</creatorcontrib><creatorcontrib>Kloostra, Ann</creatorcontrib><creatorcontrib>Lauer, Michael A</creatorcontrib><creatorcontrib>Foster, Malcom T</creatorcontrib><creatorcontrib>Fischell, Tim A</creatorcontrib><title>Role of the "dogbone" effect of balloon-expandable stents: quantitative coronary analysis of DUET and NIR stent implantation introducing a novel indexing system</title><title>The Journal of invasive cardiology</title><addtitle>J Invasive Cardiol</addtitle><description>Stent design and deployment characteristics of balloon-expandable stents may play an important role in determining both early and late outcomes of stenting. The purpose of this study was to compare the percent residual stenosis (RS) of two new-generation stent delivery systems, DUET and NIR, in patients with CAD. From September 1998 1999, a total of 100 consecutive patients with CAD receiving either a DUET (18 or 23 mm length; n = 50) or NIR stent (16 or 25 mm length; n = 50) using a 3.0 or 3.5 mm stent delivery system were compared by quantitative coronary analysis. The ability of each balloon delivery system to fully expand the stent was assessed using a new scoring index entitled the stent delivery balloon expansion ratio (SDBR; %). A high SDBR correlates with the angiographic appearance of a "dogbone" that is sometimes seen during stent deployment. A stent "scalloping" score was developed to quantitatively assess the cobblestone appearance observed angiographically with plaque protrusion after stent implantation. Mean deployment pressures were 14 +/- 2 atm (DUET) and 13 +/- 2 atm (NIR) (p=NS). Extent of elastic recoil was similar (6 +/- 5% for DUET vs. 6 +/- 4% for NIR; (p=NS). "Scalloping" was more pronounced in the DUET stent (score, 0.66 +/- 0.6 for DUET vs. 0.24 +/- 0.4 for NIR; p < 0.001). SDBR and RS were higher with DUET than with NIR stent implantation (SDBR, 15 +/- 5% vs. 12 +/- 5%; RS, 14 +/- 5% vs. 11 +/- 6%; p < 0.01). Multivariate analysis showed that SDBR and stent recoil, but not "scalloping", were associated with increased RS after stent implantation (r = 0.45 and p < 0.001 for "dogbone" effect; r = 0.39 and p < 0.001 for stent recoil).
The second-generation DUET and NIR stents and their respective delivery systems show angiographically different acute performance characteristics. Insufficient deployment of stents visualized by the "dogbone" effect plays a role in the extent of RS after stenting. The introduced angiographic indexes require further validation.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Blood Vessel Prosthesis Implantation - methods</subject><subject>Catheterization - instrumentation</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - therapy</subject><subject>Coronary Restenosis - diagnostic imaging</subject><subject>Coronary Restenosis - etiology</subject><subject>Equipment Design - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Severity of Illness Index</subject><subject>Stents</subject><subject>Treatment Outcome</subject><issn>1042-3931</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kF1LwzAUQPuguDn9CxL24FuhabK28U3m1MFQGPO55ONmRtqka9Kx_Rt_qhmbT4HDOZebe5WMcUbzlDCCR8mt9z9ZlmPC8E0ywrjCVUHYOPlduwaQ0yh8A5oqtxXOwhSB1iDDiQveNM7ZFA4dt4qLaPsANvgntBu4DSbwYPaApOud5f0Rccubozf-FL98LTYRKPSxXJ8zZNquiVmMnEXGht6pQRq7RRxZt4cmMgWHE_DHWLR3ybXmjYf7yztJNq-Lzfw9XX2-LefPq7TDeR5SppSiFGuRVRmTGJeFLGmRw4wUuqKcagwV11KIXEctFyyXqsxKqmZ0hpUgk-TxPLbr3W4AH-rWeAlN3BXc4OsSU0xKxqL4cBEH0YKqu9608dv1_0nJH7yqdMQ</recordid><startdate>200202</startdate><enddate>200202</enddate><creator>Hehrlein, Christoph</creator><creator>DeVries, Jennifer J</creator><creator>Arab, Amina</creator><creator>Haller, Scott D</creator><creator>Kloostra, Ann</creator><creator>Lauer, Michael A</creator><creator>Foster, Malcom T</creator><creator>Fischell, Tim A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200202</creationdate><title>Role of the "dogbone" effect of balloon-expandable stents: quantitative coronary analysis of DUET and NIR stent implantation introducing a novel indexing system</title><author>Hehrlein, Christoph ; DeVries, Jennifer J ; Arab, Amina ; Haller, Scott D ; Kloostra, Ann ; Lauer, Michael A ; Foster, Malcom T ; Fischell, Tim A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p122t-9ddd441fb0809c1176c7462e536f84a4f1e8afcbb2f4412b92cd7074d5451db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Blood Vessel Prosthesis Implantation - methods</topic><topic>Catheterization - instrumentation</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - therapy</topic><topic>Coronary Restenosis - diagnostic imaging</topic><topic>Coronary Restenosis - etiology</topic><topic>Equipment Design - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Severity of Illness Index</topic><topic>Stents</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hehrlein, Christoph</creatorcontrib><creatorcontrib>DeVries, Jennifer J</creatorcontrib><creatorcontrib>Arab, Amina</creatorcontrib><creatorcontrib>Haller, Scott D</creatorcontrib><creatorcontrib>Kloostra, Ann</creatorcontrib><creatorcontrib>Lauer, Michael A</creatorcontrib><creatorcontrib>Foster, Malcom T</creatorcontrib><creatorcontrib>Fischell, Tim A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of invasive cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hehrlein, Christoph</au><au>DeVries, Jennifer J</au><au>Arab, Amina</au><au>Haller, Scott D</au><au>Kloostra, Ann</au><au>Lauer, Michael A</au><au>Foster, Malcom T</au><au>Fischell, Tim A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of the "dogbone" effect of balloon-expandable stents: quantitative coronary analysis of DUET and NIR stent implantation introducing a novel indexing system</atitle><jtitle>The Journal of invasive cardiology</jtitle><addtitle>J Invasive Cardiol</addtitle><date>2002-02</date><risdate>2002</risdate><volume>14</volume><issue>2</issue><spage>59</spage><epage>65</epage><pages>59-65</pages><issn>1042-3931</issn><abstract>Stent design and deployment characteristics of balloon-expandable stents may play an important role in determining both early and late outcomes of stenting. The purpose of this study was to compare the percent residual stenosis (RS) of two new-generation stent delivery systems, DUET and NIR, in patients with CAD. From September 1998 1999, a total of 100 consecutive patients with CAD receiving either a DUET (18 or 23 mm length; n = 50) or NIR stent (16 or 25 mm length; n = 50) using a 3.0 or 3.5 mm stent delivery system were compared by quantitative coronary analysis. The ability of each balloon delivery system to fully expand the stent was assessed using a new scoring index entitled the stent delivery balloon expansion ratio (SDBR; %). A high SDBR correlates with the angiographic appearance of a "dogbone" that is sometimes seen during stent deployment. A stent "scalloping" score was developed to quantitatively assess the cobblestone appearance observed angiographically with plaque protrusion after stent implantation. Mean deployment pressures were 14 +/- 2 atm (DUET) and 13 +/- 2 atm (NIR) (p=NS). Extent of elastic recoil was similar (6 +/- 5% for DUET vs. 6 +/- 4% for NIR; (p=NS). "Scalloping" was more pronounced in the DUET stent (score, 0.66 +/- 0.6 for DUET vs. 0.24 +/- 0.4 for NIR; p < 0.001). SDBR and RS were higher with DUET than with NIR stent implantation (SDBR, 15 +/- 5% vs. 12 +/- 5%; RS, 14 +/- 5% vs. 11 +/- 6%; p < 0.01). Multivariate analysis showed that SDBR and stent recoil, but not "scalloping", were associated with increased RS after stent implantation (r = 0.45 and p < 0.001 for "dogbone" effect; r = 0.39 and p < 0.001 for stent recoil).
The second-generation DUET and NIR stents and their respective delivery systems show angiographically different acute performance characteristics. Insufficient deployment of stents visualized by the "dogbone" effect plays a role in the extent of RS after stenting. The introduced angiographic indexes require further validation.</abstract><cop>United States</cop><pmid>11818639</pmid><tpages>7</tpages></addata></record> |
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| subjects | Age Factors Aged Aged, 80 and over Blood Vessel Prosthesis Implantation - instrumentation Blood Vessel Prosthesis Implantation - methods Catheterization - instrumentation Coronary Angiography Coronary Artery Disease - complications Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - therapy Coronary Restenosis - diagnostic imaging Coronary Restenosis - etiology Equipment Design - methods Female Humans Male Middle Aged Multivariate Analysis Predictive Value of Tests Prospective Studies Severity of Illness Index Stents Treatment Outcome |
| title | Role of the "dogbone" effect of balloon-expandable stents: quantitative coronary analysis of DUET and NIR stent implantation introducing a novel indexing system |
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