Cu-Catalyzed Asymmetric Conjugate Additions of Alkylzinc Reagents to Acyclic Aliphatic Enones

Cu-catalyzed enantioselective conjugate additions to acyclic aliphatic enones are reported. The resulting enolates may be functionalized intra- and intermolecularly, leading to the formation of an additional C−C bond. The utility of the present method is not limited to reactions involving Et2Zn; a v...

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Veröffentlicht in:Journal of the American Chemical Society 2002-02, Vol.124 (5), p.779-781
Hauptverfasser: Mizutani, Hirotake, Degrado, Sylvia J, Hoveyda, Amir H
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Sprache:eng
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