Biochemical Isolation and Analysis of a Nuclear Receptor Corepressor Complex

This chapter describes the initial isolation and characterization of a core Silencing Mediator of Retinoid and Thyroid Receptors (SMRT) corepressor complex from HeLa cells. The isolation of native SMRT results in the copurification of the WD40 repeat protein—TBL1 (Transducin Beta-Like protein-1) and...

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Veröffentlicht in:	Methods in Enzymology 2003, Vol.364, p.246-257
Hauptverfasser:	Guenther, Matthew G., Lazar, Mitchell A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baculoviridae - metabolism Biochemistry - methods Cell Nucleus - metabolism HeLa Cells Histone Deacetylases - chemistry Humans Nuclear Proteins - chemistry Nuclear Receptor Co-Repressor 1 Rabbits Repressor Proteins - chemistry
Online-Zugang:	Volltext
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