Investigation of Laser-Induced Choroidal Neovascularization in the Rat

Choroidal neovascularization plays an important role in pathogenesis of age-related macular degeneration. Induction of neovascularization by laser photocoagulation in the rat fundus is an established animal model in which the effects of new therapeutic approaches are assessed. The purpose of this st...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2003-12, Vol.44 (12), p.5349-5354
Hauptverfasser:	Semkova, Irina, Peters, Swaantje, Welsandt, Gerhard, Janicki, Hanna, Jordan, Jens, Schraermeyer, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Animals Biological and medical sciences Choroid - blood supply Choroid - pathology Choroidal Neovascularization - diagnosis Choroidal Neovascularization - etiology Dextrans Disease Models, Animal Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Fluorescein Angiography - methods Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescent Antibody Technique, Indirect Horseradish Peroxidase - metabolism Immunoenzyme Techniques Laser Coagulation - adverse effects Medical sciences Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Rats Rats, Long-Evans Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit
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