Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer

The serum of cancer patients often harbors increased free DNA levels, which can potentially be used for cancer detection. Because genetic and epigenetic alterations of the adenomatous polyposis coli (APC) gene are common events in gastrointestinal tumor development, we sought to investigate the freq...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2002-01, Vol.62 (2), p.371-375
Hauptverfasser: USADEL, Henning, BRABENDER, Jan, DANENBERG, Kathy D, JERONIMO, Carmen, HARDEN, Susan, ENGLES, James, DANENBERG, Peter V, YANG, Stephen, SIDRANSKY, David
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Sprache:eng
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