Changes in serum electrolytes during treatment of patients in liver failure with molecular adsorbent recirculating system
To study the effect of MARS on serum electrolytes during liver failure. Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15-70 (median 53), treated with MARS for: 12 acute-on-chronic l...
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| Veröffentlicht in: | International journal of artificial organs 2003-10, Vol.26 (10), p.918-923 |
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| container_title | International journal of artificial organs |
| container_volume | 26 |
| creator | Doria, C Doyle, H R Mandalà, L Marino, I R Caruana, G Gruttadauria, S Lauro, A Magnone, M Scotti Foglieni, C Lamonaca, V Scott, V L |
| description | To study the effect of MARS on serum electrolytes during liver failure.
Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15-70 (median 53), treated with MARS for: 12 acute-on-chronic liver failure (52%); 4 fulminant hepatic failure (17%); 3 intractable pruritus (13%); 2 primary-non-function (9%); 2 following major liver resection (9%).
Sodium, potassium, chloride, phosphorus, calcium, and magnesium were measured in the serum, ultrafiltrate and albumin circuit before and after MARS.
A comparison of electrolyte concentrations, before and after MARS, was performed using a paired t test.
Serum electrolyte concentrations before and after MARS, while statistically significant in some cases, were very small, and of no clinical relevance.
MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis. |
| doi_str_mv | 10.1177/039139880302601008 |
| format | Article |
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Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15-70 (median 53), treated with MARS for: 12 acute-on-chronic liver failure (52%); 4 fulminant hepatic failure (17%); 3 intractable pruritus (13%); 2 primary-non-function (9%); 2 following major liver resection (9%).
Sodium, potassium, chloride, phosphorus, calcium, and magnesium were measured in the serum, ultrafiltrate and albumin circuit before and after MARS.
A comparison of electrolyte concentrations, before and after MARS, was performed using a paired t test.
Serum electrolyte concentrations before and after MARS, while statistically significant in some cases, were very small, and of no clinical relevance.
MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis.</description><identifier>ISSN: 0391-3988</identifier><identifier>EISSN: 1724-6040</identifier><identifier>DOI: 10.1177/039139880302601008</identifier><identifier>PMID: 14636008</identifier><language>eng</language><publisher>United States</publisher><subject>Adolescent ; Adult ; Aged ; Electrolytes - blood ; Female ; Hepatorenal Syndrome - blood ; Hepatorenal Syndrome - therapy ; Humans ; Liver Failure, Acute - blood ; Liver Failure, Acute - therapy ; Liver, Artificial ; Male ; Membranes, Artificial ; Middle Aged ; Retrospective Studies ; Ultrafiltration</subject><ispartof>International journal of artificial organs, 2003-10, Vol.26 (10), p.918-923</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-a2c7f0986a5bfa8e18ddb76815bc70ed235a63a104cc5803f5f4e32e9a8c9c343</citedby><cites>FETCH-LOGICAL-c332t-a2c7f0986a5bfa8e18ddb76815bc70ed235a63a104cc5803f5f4e32e9a8c9c343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14636008$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Doria, C</creatorcontrib><creatorcontrib>Doyle, H R</creatorcontrib><creatorcontrib>Mandalà, L</creatorcontrib><creatorcontrib>Marino, I R</creatorcontrib><creatorcontrib>Caruana, G</creatorcontrib><creatorcontrib>Gruttadauria, S</creatorcontrib><creatorcontrib>Lauro, A</creatorcontrib><creatorcontrib>Magnone, M</creatorcontrib><creatorcontrib>Scotti Foglieni, C</creatorcontrib><creatorcontrib>Lamonaca, V</creatorcontrib><creatorcontrib>Scott, V L</creatorcontrib><title>Changes in serum electrolytes during treatment of patients in liver failure with molecular adsorbent recirculating system</title><title>International journal of artificial organs</title><addtitle>Int J Artif Organs</addtitle><description>To study the effect of MARS on serum electrolytes during liver failure.
Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15-70 (median 53), treated with MARS for: 12 acute-on-chronic liver failure (52%); 4 fulminant hepatic failure (17%); 3 intractable pruritus (13%); 2 primary-non-function (9%); 2 following major liver resection (9%).
Sodium, potassium, chloride, phosphorus, calcium, and magnesium were measured in the serum, ultrafiltrate and albumin circuit before and after MARS.
A comparison of electrolyte concentrations, before and after MARS, was performed using a paired t test.
Serum electrolyte concentrations before and after MARS, while statistically significant in some cases, were very small, and of no clinical relevance.
MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Electrolytes - blood</subject><subject>Female</subject><subject>Hepatorenal Syndrome - blood</subject><subject>Hepatorenal Syndrome - therapy</subject><subject>Humans</subject><subject>Liver Failure, Acute - blood</subject><subject>Liver Failure, Acute - therapy</subject><subject>Liver, Artificial</subject><subject>Male</subject><subject>Membranes, Artificial</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Ultrafiltration</subject><issn>0391-3988</issn><issn>1724-6040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT1PwzAQhi0EoqXwBxiQJ7aAv-I4I6r4kiqxwBw5zrk1cpJiO6D-exJaiYGB6U6n53mHexG6pOSG0qK4JbykvFSKcMIkoYSoIzSnBROZJIIco_kEZBMxQ2cxvhNCpRD5KZpRIbkc-TnaLTe6W0PErsMRwtBi8GBS6P0ujddmCK5b4xRApxa6hHuLtzq5cf1RvPuEgK12fgiAv1za4LYfAwavA9ZN7EM9WQGMC9MxTWlxFxO05-jEah_h4jAX6O3h_nX5lK1eHp-Xd6vMcM5SppkpLCmV1HlttQKqmqYupKJ5bQoCDeO5llxTIozJx1fY3ArgDEqtTGm44At0vc_dhv5jgJiq1kUD3usO-iFWBRWE5aL8F6Ql51wwOoJsD5rQxxjAVtvgWh12FSXV1Ez1t5lRujqkD3ULza9yqIJ_A35bi6U</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>Doria, C</creator><creator>Doyle, H R</creator><creator>Mandalà, L</creator><creator>Marino, I R</creator><creator>Caruana, G</creator><creator>Gruttadauria, S</creator><creator>Lauro, A</creator><creator>Magnone, M</creator><creator>Scotti Foglieni, C</creator><creator>Lamonaca, V</creator><creator>Scott, V L</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20031001</creationdate><title>Changes in serum electrolytes during treatment of patients in liver failure with molecular adsorbent recirculating system</title><author>Doria, C ; Doyle, H R ; Mandalà, L ; Marino, I R ; Caruana, G ; Gruttadauria, S ; Lauro, A ; Magnone, M ; Scotti Foglieni, C ; Lamonaca, V ; Scott, V L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-a2c7f0986a5bfa8e18ddb76815bc70ed235a63a104cc5803f5f4e32e9a8c9c343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Electrolytes - blood</topic><topic>Female</topic><topic>Hepatorenal Syndrome - blood</topic><topic>Hepatorenal Syndrome - therapy</topic><topic>Humans</topic><topic>Liver Failure, Acute - blood</topic><topic>Liver Failure, Acute - therapy</topic><topic>Liver, Artificial</topic><topic>Male</topic><topic>Membranes, Artificial</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Ultrafiltration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Doria, C</creatorcontrib><creatorcontrib>Doyle, H R</creatorcontrib><creatorcontrib>Mandalà, L</creatorcontrib><creatorcontrib>Marino, I R</creatorcontrib><creatorcontrib>Caruana, G</creatorcontrib><creatorcontrib>Gruttadauria, S</creatorcontrib><creatorcontrib>Lauro, A</creatorcontrib><creatorcontrib>Magnone, M</creatorcontrib><creatorcontrib>Scotti Foglieni, C</creatorcontrib><creatorcontrib>Lamonaca, V</creatorcontrib><creatorcontrib>Scott, V L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of artificial organs</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Doria, C</au><au>Doyle, H R</au><au>Mandalà, L</au><au>Marino, I R</au><au>Caruana, G</au><au>Gruttadauria, S</au><au>Lauro, A</au><au>Magnone, M</au><au>Scotti Foglieni, C</au><au>Lamonaca, V</au><au>Scott, V L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes in serum electrolytes during treatment of patients in liver failure with molecular adsorbent recirculating system</atitle><jtitle>International journal of artificial organs</jtitle><addtitle>Int J Artif Organs</addtitle><date>2003-10-01</date><risdate>2003</risdate><volume>26</volume><issue>10</issue><spage>918</spage><epage>923</epage><pages>918-923</pages><issn>0391-3988</issn><eissn>1724-6040</eissn><abstract>To study the effect of MARS on serum electrolytes during liver failure.
Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15-70 (median 53), treated with MARS for: 12 acute-on-chronic liver failure (52%); 4 fulminant hepatic failure (17%); 3 intractable pruritus (13%); 2 primary-non-function (9%); 2 following major liver resection (9%).
Sodium, potassium, chloride, phosphorus, calcium, and magnesium were measured in the serum, ultrafiltrate and albumin circuit before and after MARS.
A comparison of electrolyte concentrations, before and after MARS, was performed using a paired t test.
Serum electrolyte concentrations before and after MARS, while statistically significant in some cases, were very small, and of no clinical relevance.
MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis.</abstract><cop>United States</cop><pmid>14636008</pmid><doi>10.1177/039139880302601008</doi><tpages>6</tpages></addata></record> |
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| ispartof | International journal of artificial organs, 2003-10, Vol.26 (10), p.918-923 |
| issn | 0391-3988 1724-6040 |
| language | eng |
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| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Adolescent Adult Aged Electrolytes - blood Female Hepatorenal Syndrome - blood Hepatorenal Syndrome - therapy Humans Liver Failure, Acute - blood Liver Failure, Acute - therapy Liver, Artificial Male Membranes, Artificial Middle Aged Retrospective Studies Ultrafiltration |
| title | Changes in serum electrolytes during treatment of patients in liver failure with molecular adsorbent recirculating system |
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