Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise
Interscapular brown adipose tissue (IBAT) activity is controlled by the sympathetic nervous system, and factors that influence thermogenesis appear to act centrally to modify the sympathetic outflow to IBAT. Cold exposure produces a rise in IBAT temperature as a result of the increase in sympathetic...
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| Veröffentlicht in: | Physiology & behavior 2003-11, Vol.80 (2), p.399-403 |
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| creator | Sullo, Alessio Brizzi, Guglielmo Maffulli, Nicola |
| description | Interscapular brown adipose tissue (IBAT) activity is controlled by the sympathetic nervous system, and factors that influence thermogenesis appear to act centrally to modify the sympathetic outflow to IBAT. Cold exposure produces a rise in IBAT temperature as a result of the increase in sympathetic outflow to IBAT. This is associated with an increased thyroid activity. 3,5,3′-triiodothyronine (T
3) and T
4 levels increase during strenuous exercise, and, at the end of the exercise bout, a decrease of T
3 and T
4 levels, with an increase in TSH during the following 4–5 days, is seen. We evaluated the effect of strenuous exercise on 5′-deiodinase (5′-D) activity in IBAT in normal environmental conditions and after short (30 min) cold exposure. 5′-D activity is lower in rats at basal condition. Short cold exposure (SCE) increases 5′-D in IBAT both in exercising rats and in sedentary rats. However, this increase is lower in exercising animals. Strenuous exercise can reduce 5′-D activity in normal environmental conditions and after SCE. Probably, other compensatory mechanisms of heat production are active in exercising rodents. |
| doi_str_mv | 10.1016/j.physbeh.2003.09.005 |
| format | Article |
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3) and T
4 levels increase during strenuous exercise, and, at the end of the exercise bout, a decrease of T
3 and T
4 levels, with an increase in TSH during the following 4–5 days, is seen. We evaluated the effect of strenuous exercise on 5′-deiodinase (5′-D) activity in IBAT in normal environmental conditions and after short (30 min) cold exposure. 5′-D activity is lower in rats at basal condition. Short cold exposure (SCE) increases 5′-D in IBAT both in exercising rats and in sedentary rats. However, this increase is lower in exercising animals. Strenuous exercise can reduce 5′-D activity in normal environmental conditions and after SCE. Probably, other compensatory mechanisms of heat production are active in exercising rodents.</description><identifier>ISSN: 0031-9384</identifier><identifier>EISSN: 1873-507X</identifier><identifier>DOI: 10.1016/j.physbeh.2003.09.005</identifier><identifier>PMID: 14637241</identifier><language>eng</language><publisher>Cambridge: Elsevier Inc</publisher><subject>Adipose Tissue, Brown - metabolism ; Animals ; Biological and medical sciences ; Body Temperature Regulation ; Brown adipose tissue ; Cold Temperature ; Deiodinase activity ; Fundamental and applied biological sciences. Psychology ; Iodide Peroxidase - metabolism ; Male ; Physical Conditioning, Animal ; Radioimmunoassay ; Rats ; Rats, Sprague-Dawley ; Thermogenesis ; Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects ; Thyroid hormone ; Thyrotropin - blood ; Thyroxine - blood ; Time Factors ; Training ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>Physiology & behavior, 2003-11, Vol.80 (2), p.399-403</ispartof><rights>2003 Elsevier Inc.</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-3b4a95f6810d1d3e13af793d8db993c28f3b32db5b50ebf07f01f2b9e8c37e6e3</citedby><cites>FETCH-LOGICAL-c422t-3b4a95f6810d1d3e13af793d8db993c28f3b32db5b50ebf07f01f2b9e8c37e6e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0031938403002968$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15369263$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14637241$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sullo, Alessio</creatorcontrib><creatorcontrib>Brizzi, Guglielmo</creatorcontrib><creatorcontrib>Maffulli, Nicola</creatorcontrib><title>Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise</title><title>Physiology & behavior</title><addtitle>Physiol Behav</addtitle><description>Interscapular brown adipose tissue (IBAT) activity is controlled by the sympathetic nervous system, and factors that influence thermogenesis appear to act centrally to modify the sympathetic outflow to IBAT. Cold exposure produces a rise in IBAT temperature as a result of the increase in sympathetic outflow to IBAT. This is associated with an increased thyroid activity. 3,5,3′-triiodothyronine (T
3) and T
4 levels increase during strenuous exercise, and, at the end of the exercise bout, a decrease of T
3 and T
4 levels, with an increase in TSH during the following 4–5 days, is seen. We evaluated the effect of strenuous exercise on 5′-deiodinase (5′-D) activity in IBAT in normal environmental conditions and after short (30 min) cold exposure. 5′-D activity is lower in rats at basal condition. Short cold exposure (SCE) increases 5′-D in IBAT both in exercising rats and in sedentary rats. However, this increase is lower in exercising animals. Strenuous exercise can reduce 5′-D activity in normal environmental conditions and after SCE. Probably, other compensatory mechanisms of heat production are active in exercising rodents.</description><subject>Adipose Tissue, Brown - metabolism</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Body Temperature Regulation</subject><subject>Brown adipose tissue</subject><subject>Cold Temperature</subject><subject>Deiodinase activity</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Iodide Peroxidase - metabolism</subject><subject>Male</subject><subject>Physical Conditioning, Animal</subject><subject>Radioimmunoassay</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Thermogenesis</subject><subject>Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects</subject><subject>Thyroid hormone</subject><subject>Thyrotropin - blood</subject><subject>Thyroxine - blood</subject><subject>Time Factors</subject><subject>Training</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0031-9384</issn><issn>1873-507X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcuO1DAQRS0EYpqBTwB5A7sEP5I4XiE0PKWR2IDEzvKjTLuVjoPtzNB_j1sdaZbjTS3q3HKpDkKvKWkpocP7Q7vsT9nAvmWE8JbIlpD-CdrRUfCmJ-L3U7SrDdpIPnZX6EXOB1If7_hzdEW7gQvW0R1aPkGILsy6hPkP1raEu1BOOMy47AGbFO9nrF1YYgZcQs4r4Ohx0iVjH6cp3p9jeR9TwTZODsO_iq4JsPYFEs4lwbzGNdcGJBsyvETPvJ4yvNrqNfr15fPPm2_N7Y-v328-3ja2Y6w03HRa9n4YKXHUcaBceyG5G52Rkls2em44c6Y3PQHjifCEemYkjJYLGIBfo3eXuUuKf1fIRR1DtjBNeoa6jxK0I6wbyKMgFYLIse8q2F9Am2LOCbxaUjjqdFKUqLMTdVCbE3V2oohU1UnNvdk-WM0R3ENqk1CBtxugs9WTT3qul3rgej5INvDKfbhwUO92FyCpbAPMFlxIYItyMTyyyn-Oiq_h</recordid><startdate>20031101</startdate><enddate>20031101</enddate><creator>Sullo, Alessio</creator><creator>Brizzi, Guglielmo</creator><creator>Maffulli, Nicola</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>20031101</creationdate><title>Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise</title><author>Sullo, Alessio ; Brizzi, Guglielmo ; Maffulli, Nicola</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-3b4a95f6810d1d3e13af793d8db993c28f3b32db5b50ebf07f01f2b9e8c37e6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adipose Tissue, Brown - metabolism</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Body Temperature Regulation</topic><topic>Brown adipose tissue</topic><topic>Cold Temperature</topic><topic>Deiodinase activity</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Iodide Peroxidase - metabolism</topic><topic>Male</topic><topic>Physical Conditioning, Animal</topic><topic>Radioimmunoassay</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Thermogenesis</topic><topic>Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects</topic><topic>Thyroid hormone</topic><topic>Thyrotropin - blood</topic><topic>Thyroxine - blood</topic><topic>Time Factors</topic><topic>Training</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sullo, Alessio</creatorcontrib><creatorcontrib>Brizzi, Guglielmo</creatorcontrib><creatorcontrib>Maffulli, Nicola</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Physiology & behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sullo, Alessio</au><au>Brizzi, Guglielmo</au><au>Maffulli, Nicola</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise</atitle><jtitle>Physiology & behavior</jtitle><addtitle>Physiol Behav</addtitle><date>2003-11-01</date><risdate>2003</risdate><volume>80</volume><issue>2</issue><spage>399</spage><epage>403</epage><pages>399-403</pages><issn>0031-9384</issn><eissn>1873-507X</eissn><abstract>Interscapular brown adipose tissue (IBAT) activity is controlled by the sympathetic nervous system, and factors that influence thermogenesis appear to act centrally to modify the sympathetic outflow to IBAT. Cold exposure produces a rise in IBAT temperature as a result of the increase in sympathetic outflow to IBAT. This is associated with an increased thyroid activity. 3,5,3′-triiodothyronine (T
3) and T
4 levels increase during strenuous exercise, and, at the end of the exercise bout, a decrease of T
3 and T
4 levels, with an increase in TSH during the following 4–5 days, is seen. We evaluated the effect of strenuous exercise on 5′-deiodinase (5′-D) activity in IBAT in normal environmental conditions and after short (30 min) cold exposure. 5′-D activity is lower in rats at basal condition. Short cold exposure (SCE) increases 5′-D in IBAT both in exercising rats and in sedentary rats. However, this increase is lower in exercising animals. Strenuous exercise can reduce 5′-D activity in normal environmental conditions and after SCE. Probably, other compensatory mechanisms of heat production are active in exercising rodents.</abstract><cop>Cambridge</cop><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>14637241</pmid><doi>10.1016/j.physbeh.2003.09.005</doi><tpages>5</tpages></addata></record> |
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| subjects | Adipose Tissue, Brown - metabolism Animals Biological and medical sciences Body Temperature Regulation Brown adipose tissue Cold Temperature Deiodinase activity Fundamental and applied biological sciences. Psychology Iodide Peroxidase - metabolism Male Physical Conditioning, Animal Radioimmunoassay Rats Rats, Sprague-Dawley Thermogenesis Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects Thyroid hormone Thyrotropin - blood Thyroxine - blood Time Factors Training Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise |
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