Scintigraphy using a technetium 99m‐labelled anti‐E‐selectin Fab fragment in rheumatoid arthritis

Objective. We previously described a novel radiolabelled monoclonal antibody (1.2B6), which reacts with porcine E‐selectin, for targeting activated endothelium as a means of imaging inflammatory disorders, and presented initial clinical work based on 111In‐labelled antibody. The aim of the present s...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2002-01, Vol.41 (1), p.53-61
Hauptverfasser:	Jamar, F., Houssiau, F. A., Devogelaer, J.‐P., Chapman, P. T., Haskard, D. O., Beaujean, V., Beckers, C., Manicourt, D.‐H., Peters, A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Arthritis, Rheumatoid - diagnostic imaging Biological and medical sciences E-Selectin - metabolism Endothelium E‐selectin Female Humans Immunoglobulin Fab Fragments Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Monoclonal antibody Osteoarticular system. Muscles Probability Prospective Studies Radioisotopes Radionuclide Imaging Radionuclide investigations Rheumatoid arthritis ROC Curve Sensitivity and Specificity Technetium Technetium Tc 99m Medronate - analogs & derivatives
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