Topical administration of the nitric oxide donor glyceryl trinitrate modifies the structural and biomechanical properties of ovine articular cartilage

Objective: To examine the effect of topical administration of glyceryl trinitrate (GTN), an exogenous nitric oxide (NO) donor, on the structural and biomechanical properties of uncalcified articular cartilage (UCC) in aged ewes. Design: Twelve ewes were used for this study. Six of these were treated...

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Veröffentlicht in:Osteoarthritis and cartilage 2003-12, Vol.11 (12), p.872-878
Hauptverfasser: Cake, M.A, Appleyard, R.C, Read, R.A, Ghosh, P, Swain, M.V, Murrell, G.C
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Sprache:eng
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