Myeloid hematopoietic growth factors and their role in prevention and/or treatment of neonatal sepsis

Sepsis continues to be an important cause of morbidity and mortality among both full-term and preterm infants, secondary to an immaturity in neonatal host defense. The incidence of neonatal sepsis ranges from 30% in very low birth weight infants to 0.4% in preterm neonates and 0.1% in term neonates....

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Veröffentlicht in:	Transfusion medicine reviews 2002, Vol.16 (1), p.11-24
Hauptverfasser:	Parravicini, Elvira, Ven, Carmella van de, Anderson, Lauren, Cairo, Mitchell S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Animals, Newborn Chemotaxis, Leukocyte - drug effects Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Cohort Studies Cross Infection - drug therapy Cross Infection - epidemiology Disease Susceptibility Double-Blind Method Drug Evaluation, Preclinical Female Granulocyte Colony-Stimulating Factor - biosynthesis Granulocyte Colony-Stimulating Factor - genetics Granulocyte Colony-Stimulating Factor - pharmacology Granulocyte Colony-Stimulating Factor - therapeutic use Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis Granulocyte-Macrophage Colony-Stimulating Factor - genetics Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use Hematopoiesis - drug effects Hematopoiesis - physiology Hematopoietic Cell Growth Factors - biosynthesis Hematopoietic Cell Growth Factors - genetics Hematopoietic Cell Growth Factors - pharmacology Hematopoietic Cell Growth Factors - therapeutic use Humans Immunocompetence - drug effects Incidence Infant Infant, Low Birth Weight Infant, Newborn Infant, Premature Interleukins - pharmacology Interleukins - therapeutic use Macrophage Colony-Stimulating Factor - biosynthesis Macrophage Colony-Stimulating Factor - genetics Macrophage Colony-Stimulating Factor - pharmacology Macrophage Colony-Stimulating Factor - therapeutic use Male Mice Myeloid Cells - cytology Myeloid Cells - drug effects Neutrophils - drug effects Phagocytosis - drug effects Pregnancy Pregnancy Complications, Infectious Randomized Controlled Trials as Topic Rats Recombinant Proteins - therapeutic use Respiratory Burst - drug effects Sepsis - congenital Sepsis - drug therapy Sepsis - epidemiology Sepsis - prevention & control Stem Cell Factor - biosynthesis Stem Cell Factor - genetics Stem Cell Factor - pharmacology Stem Cell Factor - therapeutic use
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