Use of collagen sponge incorporating transforming growth factor-beta1 to promote bone repair in skull defects in rabbits

The objective of this study was to evaluate the potential of collagen sponge incorporating transforming growth factor-beta1 (TGF-beta1) to enhance bone repair. The collagen sponge was prepared by freeze-drying aqueous foamed collagen solution. Thermal cross-linking was performed in a vacuum at 140 d...

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Veröffentlicht in:	Biomaterials 2002-02, Vol.23 (4), p.1003-1010
Hauptverfasser:	Ueda, Hiroki, Hong, Liu, Yamamoto, Masaya, Shigeno, Keiji, Inoue, Masatoshi, Toba, Toshinari, Yoshitani, Makoto, Nakamura, Tatsuo, Tabata, Yasuhiko, Shimizu, Yasuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials Collagen - ultrastructure Delayed-Action Preparations Drug Carriers Female Fracture Healing - drug effects Materials Testing Mice Microscopy, Electron, Scanning Rabbits Recombinant Proteins - administration & dosage Skull Fractures - drug therapy Skull Fractures - pathology Surgical Sponges Transforming Growth Factor beta - administration & dosage Transforming Growth Factor beta1
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