ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells

We determined the distribution of ET(A) and ET(B) receptors in pulmonary arteries from pulmonary hypertensive patients and control subjects, using in vitro autoradiography, and investigated their role in mediating the proliferative effects of endothelin-1 (ET-1) on distal human pulmonary artery smoo...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2002-02, Vol.165 (3), p.398-405
Hauptverfasser:	Davie, Neil, Haleen, Stephen J, Upton, Paul D, Polak, Julia M, Yacoub, Magdi H, Morrell, Nicholas W, Wharton, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell Division Female Humans Male Middle Aged Muscle, Smooth, Vascular - chemistry Muscle, Smooth, Vascular - cytology Pulmonary Artery - chemistry Pulmonary Artery - cytology Receptors, Endothelin - analysis Receptors, Endothelin - physiology
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