Adeno-associated virus type 5: Transduction efficiency and cell-type specificity in the primate retina

Gene transfer using adeno-associated viruses (AAVs) has been effective for treating inherited retinal diseases in animal models. Further evaluation in primates must be performed prior to clinical application, however, because of the difference between the retina of the primate and those of other ani...

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Veröffentlicht in:Human gene therapy 2003-11, Vol.14 (17), p.1663-1671
Hauptverfasser: LOTERY, Andrew J, YANG, Grace S, MULLINS, Robert F, RUSSELL, Stephen R, SCHMIDT, Michael, STONE, Edwin M, LINDBLOOM, Jonathan D, CHIORINI, John A, KOTIN, Robert M, DAVIDSON, Beverly L
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Sprache:eng
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