Variance-Component Analysis of Obesity in Type 2 Diabetes Confirms Loci on Chromosomes 1q and 11q

To study genetic loci influencing obesity in nuclear families with type 2 diabetes, we performed a genome‐wide screen with 325 microsatellite markers that had an average spacing of 11 cM and a mean heterozygosity of ∼75% covering all 22 autosomes. Genotype data were obtained from 562 individuals fro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2003-11, Vol.11 (11), p.1290-1294
Hauptverfasser:	Tilburg, Jonathan H.O., Sandkuijl, Lodewijk A., Strengman, Eric, Pearson, Peter L., Haeften, Timon W., Wijmenga, Cisca
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis of Variance Body Mass Index Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 11 Diabetes Mellitus - genetics Diabetes Mellitus, Type 2 - genetics Female genetics genome‐wide screening Genotype Heterozygote Humans Lod Score Male Microsatellite Repeats Middle Aged Obesity Quantitative Trait Loci type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!