Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations
PURPOSE:To compare the diagnostic power of different software implementations for the quantification of coronary artery calcium. MATERIALS AND METHODS:Electron beam computed tomography was performed in 109 heart transplant recipients at the same time as catheter coronary angiography and intracoronar...
Gespeichert in:
| Veröffentlicht in: | Investigative radiology 2003-12, Vol.38 (12), p.761-768 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 768 |
|---|---|
| container_issue | 12 |
| container_start_page | 761 |
| container_title | Investigative radiology |
| container_volume | 38 |
| creator | Knollmann, Friedrich D Helmig, Klaus Kapell, Susanne Hummel, Manfred Bocksch, Wolfgang Hetzer, Roland Felix, Roland |
| description | PURPOSE:To compare the diagnostic power of different software implementations for the quantification of coronary artery calcium.
MATERIALS AND METHODS:Electron beam computed tomography was performed in 109 heart transplant recipients at the same time as catheter coronary angiography and intracoronary ultrasound. Electron beam computed tomography images were analyzed by 3 software packages marketed for the quantification of coronary calcifications using the same software settings, and the resultant calcium scores correlated with the invasive reference methods by Bland-Altman plots and analysis of the receiver operating characteristics.
RESULTS:Although all scoring systems displayed close correlations upon regression analysis (r = 0.94–0.99), their ability to detect disease as per the invasive reference method varied significantly in some instances. The area under the ROC curve varied between Az = 0.78 and 0.85 for the detection of coronary artery stenosis upon coronary angiography (P = 0.05–0.13), and between Az = 0.75 and 0.83 for the detection of accelerated intimal proliferation (P = 0.03–0.18).
CONCLUSIONS:Different software implementations for the quantification of coronary artery calcium load may display diagnostically relevant differences in spite of close direct correlation. |
| doi_str_mv | 10.1097/01.rli.0000084257.43062.c2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71388910</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71388910</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3033-14167e832919dafb468baed1823c69cde626a2fe7a796e82fe9ed2e5619ebf713</originalsourceid><addsrcrecordid>eNpFkMtu2zAQRYmgQeKk-YVA6KI7qcOHKdE7w20SAwG6SLrphqCpYaKWEl1SgpG_L_0AzAWHuDgzAx5CvlCoKKj6G9Aq-q6C_WkEm9eV4CBZZdkFmdE5lyUwCp_IDIBBqZSS1-QmpT8ZZzXwK3JNhWR1o_iM_F6FGAYTP4plHDGXlfG2m_rixYbYDW-L4ntn3oaQxs4WS2unaOxHEVyOncOIw1i8BDfuTMRi3W899jkyYxeG9JlcOuMT3p3qLfn18ON19VQ-_3xcr5bPpeXAeUkFlTU2nCmqWuM2QjYbgy1tGLdS2RYlk4Y5rE2tJDb5pbBlOJdU4cbVlN-Sr8e52xj-TZhG3XfJovdmwDAlnZGmURQyuDiCNoaUIjq9jV2f_64p6L1ZDVRns_psVh_Masty8_1py7TpsT23nlRmQByBXfDZZPrrpx1G_Y7Gj--HkUIwUTIATvMF5T7i_D_tDYZd</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71388910</pqid></control><display><type>article</type><title>Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Knollmann, Friedrich D ; Helmig, Klaus ; Kapell, Susanne ; Hummel, Manfred ; Bocksch, Wolfgang ; Hetzer, Roland ; Felix, Roland</creator><creatorcontrib>Knollmann, Friedrich D ; Helmig, Klaus ; Kapell, Susanne ; Hummel, Manfred ; Bocksch, Wolfgang ; Hetzer, Roland ; Felix, Roland</creatorcontrib><description>PURPOSE:To compare the diagnostic power of different software implementations for the quantification of coronary artery calcium.
MATERIALS AND METHODS:Electron beam computed tomography was performed in 109 heart transplant recipients at the same time as catheter coronary angiography and intracoronary ultrasound. Electron beam computed tomography images were analyzed by 3 software packages marketed for the quantification of coronary calcifications using the same software settings, and the resultant calcium scores correlated with the invasive reference methods by Bland-Altman plots and analysis of the receiver operating characteristics.
RESULTS:Although all scoring systems displayed close correlations upon regression analysis (r = 0.94–0.99), their ability to detect disease as per the invasive reference method varied significantly in some instances. The area under the ROC curve varied between Az = 0.78 and 0.85 for the detection of coronary artery stenosis upon coronary angiography (P = 0.05–0.13), and between Az = 0.75 and 0.83 for the detection of accelerated intimal proliferation (P = 0.03–0.18).
CONCLUSIONS:Different software implementations for the quantification of coronary artery calcium load may display diagnostically relevant differences in spite of close direct correlation.</description><identifier>ISSN: 0020-9996</identifier><identifier>EISSN: 1536-0210</identifier><identifier>DOI: 10.1097/01.rli.0000084257.43062.c2</identifier><identifier>PMID: 14627893</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Algorithms ; Calcinosis - diagnostic imaging ; Coronary Artery Disease - diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; ROC Curve ; Sensitivity and Specificity ; Software Validation ; Tomography, X-Ray Computed</subject><ispartof>Investigative radiology, 2003-12, Vol.38 (12), p.761-768</ispartof><rights>2003 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3033-14167e832919dafb468baed1823c69cde626a2fe7a796e82fe9ed2e5619ebf713</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14627893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Knollmann, Friedrich D</creatorcontrib><creatorcontrib>Helmig, Klaus</creatorcontrib><creatorcontrib>Kapell, Susanne</creatorcontrib><creatorcontrib>Hummel, Manfred</creatorcontrib><creatorcontrib>Bocksch, Wolfgang</creatorcontrib><creatorcontrib>Hetzer, Roland</creatorcontrib><creatorcontrib>Felix, Roland</creatorcontrib><title>Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations</title><title>Investigative radiology</title><addtitle>Invest Radiol</addtitle><description>PURPOSE:To compare the diagnostic power of different software implementations for the quantification of coronary artery calcium.
MATERIALS AND METHODS:Electron beam computed tomography was performed in 109 heart transplant recipients at the same time as catheter coronary angiography and intracoronary ultrasound. Electron beam computed tomography images were analyzed by 3 software packages marketed for the quantification of coronary calcifications using the same software settings, and the resultant calcium scores correlated with the invasive reference methods by Bland-Altman plots and analysis of the receiver operating characteristics.
RESULTS:Although all scoring systems displayed close correlations upon regression analysis (r = 0.94–0.99), their ability to detect disease as per the invasive reference method varied significantly in some instances. The area under the ROC curve varied between Az = 0.78 and 0.85 for the detection of coronary artery stenosis upon coronary angiography (P = 0.05–0.13), and between Az = 0.75 and 0.83 for the detection of accelerated intimal proliferation (P = 0.03–0.18).
CONCLUSIONS:Different software implementations for the quantification of coronary artery calcium load may display diagnostically relevant differences in spite of close direct correlation.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Algorithms</subject><subject>Calcinosis - diagnostic imaging</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>ROC Curve</subject><subject>Sensitivity and Specificity</subject><subject>Software Validation</subject><subject>Tomography, X-Ray Computed</subject><issn>0020-9996</issn><issn>1536-0210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtu2zAQRYmgQeKk-YVA6KI7qcOHKdE7w20SAwG6SLrphqCpYaKWEl1SgpG_L_0AzAWHuDgzAx5CvlCoKKj6G9Aq-q6C_WkEm9eV4CBZZdkFmdE5lyUwCp_IDIBBqZSS1-QmpT8ZZzXwK3JNhWR1o_iM_F6FGAYTP4plHDGXlfG2m_rixYbYDW-L4ntn3oaQxs4WS2unaOxHEVyOncOIw1i8BDfuTMRi3W899jkyYxeG9JlcOuMT3p3qLfn18ON19VQ-_3xcr5bPpeXAeUkFlTU2nCmqWuM2QjYbgy1tGLdS2RYlk4Y5rE2tJDb5pbBlOJdU4cbVlN-Sr8e52xj-TZhG3XfJovdmwDAlnZGmURQyuDiCNoaUIjq9jV2f_64p6L1ZDVRns_psVh_Masty8_1py7TpsT23nlRmQByBXfDZZPrrpx1G_Y7Gj--HkUIwUTIATvMF5T7i_D_tDYZd</recordid><startdate>200312</startdate><enddate>200312</enddate><creator>Knollmann, Friedrich D</creator><creator>Helmig, Klaus</creator><creator>Kapell, Susanne</creator><creator>Hummel, Manfred</creator><creator>Bocksch, Wolfgang</creator><creator>Hetzer, Roland</creator><creator>Felix, Roland</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200312</creationdate><title>Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations</title><author>Knollmann, Friedrich D ; Helmig, Klaus ; Kapell, Susanne ; Hummel, Manfred ; Bocksch, Wolfgang ; Hetzer, Roland ; Felix, Roland</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3033-14167e832919dafb468baed1823c69cde626a2fe7a796e82fe9ed2e5619ebf713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Algorithms</topic><topic>Calcinosis - diagnostic imaging</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>ROC Curve</topic><topic>Sensitivity and Specificity</topic><topic>Software Validation</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Knollmann, Friedrich D</creatorcontrib><creatorcontrib>Helmig, Klaus</creatorcontrib><creatorcontrib>Kapell, Susanne</creatorcontrib><creatorcontrib>Hummel, Manfred</creatorcontrib><creatorcontrib>Bocksch, Wolfgang</creatorcontrib><creatorcontrib>Hetzer, Roland</creatorcontrib><creatorcontrib>Felix, Roland</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Investigative radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Knollmann, Friedrich D</au><au>Helmig, Klaus</au><au>Kapell, Susanne</au><au>Hummel, Manfred</au><au>Bocksch, Wolfgang</au><au>Hetzer, Roland</au><au>Felix, Roland</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations</atitle><jtitle>Investigative radiology</jtitle><addtitle>Invest Radiol</addtitle><date>2003-12</date><risdate>2003</risdate><volume>38</volume><issue>12</issue><spage>761</spage><epage>768</epage><pages>761-768</pages><issn>0020-9996</issn><eissn>1536-0210</eissn><abstract>PURPOSE:To compare the diagnostic power of different software implementations for the quantification of coronary artery calcium.
MATERIALS AND METHODS:Electron beam computed tomography was performed in 109 heart transplant recipients at the same time as catheter coronary angiography and intracoronary ultrasound. Electron beam computed tomography images were analyzed by 3 software packages marketed for the quantification of coronary calcifications using the same software settings, and the resultant calcium scores correlated with the invasive reference methods by Bland-Altman plots and analysis of the receiver operating characteristics.
RESULTS:Although all scoring systems displayed close correlations upon regression analysis (r = 0.94–0.99), their ability to detect disease as per the invasive reference method varied significantly in some instances. The area under the ROC curve varied between Az = 0.78 and 0.85 for the detection of coronary artery stenosis upon coronary angiography (P = 0.05–0.13), and between Az = 0.75 and 0.83 for the detection of accelerated intimal proliferation (P = 0.03–0.18).
CONCLUSIONS:Different software implementations for the quantification of coronary artery calcium load may display diagnostically relevant differences in spite of close direct correlation.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>14627893</pmid><doi>10.1097/01.rli.0000084257.43062.c2</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0020-9996 |
| ispartof | Investigative radiology, 2003-12, Vol.38 (12), p.761-768 |
| issn | 0020-9996 1536-0210 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71388910 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Aged Algorithms Calcinosis - diagnostic imaging Coronary Artery Disease - diagnostic imaging Female Humans Male Middle Aged ROC Curve Sensitivity and Specificity Software Validation Tomography, X-Ray Computed |
| title | Coronary Artery Calcium Scoring: Diagnostic Accuracy of Different Software Implementations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T23%3A54%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Coronary%20Artery%20Calcium%20Scoring:%20Diagnostic%20Accuracy%20of%20Different%20Software%20Implementations&rft.jtitle=Investigative%20radiology&rft.au=Knollmann,%20Friedrich%20D&rft.date=2003-12&rft.volume=38&rft.issue=12&rft.spage=761&rft.epage=768&rft.pages=761-768&rft.issn=0020-9996&rft.eissn=1536-0210&rft_id=info:doi/10.1097/01.rli.0000084257.43062.c2&rft_dat=%3Cproquest_cross%3E71388910%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71388910&rft_id=info:pmid/14627893&rfr_iscdi=true |