Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire

Here we provide a description of lymphocyte populations in human lymph nodes (LN) with a special emphasis on the CD4+ lymphocyte population constitutively expressing CD25 at a high level and endowed with immunoregulatory properties [T regulatory (Treg) cells]. Lymph nodes were analysed by multicolou...

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Veröffentlicht in:	Immunology 2003-11, Vol.110 (3), p.304-312
Hauptverfasser:	Battaglia, Alessandra, Ferrandina, Gabriella, Buzzonetti, Alessia, Malinconico, Paolo, Legge, Francesco, Salutari, Vanda, Scambia, Giovanni, Fattorossi, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, CD Antigens, Differentiation - metabolism CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology CTLA-4 Antigen Female Humans Immunophenotyping Lymph Nodes - immunology Lymphocyte Subsets - immunology Middle Aged Receptors, Antigen, T-Cell, alpha-beta - metabolism Receptors, Interleukin-2 - metabolism
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