Outer membrane protein 100, a versatile virulence factor of Actinobacillus actinomycetemcomitans

Summary Actinobacillus actinomycetemcomitans (Aa) is one of the pathogenic bacteria involved in periodontal diseases. We have previously identified six major outer membrane proteins (Omps) of Aa Y4. Among them is an Omp with high molecular mass, designated Omp100, which has homology to a variety of...

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Veröffentlicht in:	Molecular microbiology 2003-11, Vol.50 (4), p.1125-1139
Hauptverfasser:	Asakawa, Ryuji, Komatsuzawa, Hitoshi, Kawai, Toshihisa, Yamada, Sakuo, Goncalves, Reginaldo Bruno, Izumi, Shunsuke, Fujiwara, Tamaki, Nakano, Yoshio, Suzuki, Nao, Uchida, Yuushi, Ouhara, Kazuhisa, Shiba, Hideki, Taubman, Martin A., Kurihara, Hidemi, Sugai, Motoyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacillus actinomycetemcomitans Actinobacillus Infections - microbiology Aggregatibacter actinomycetemcomitans - metabolism Aggregatibacter actinomycetemcomitans - pathogenicity Aggregatibacter actinomycetemcomitans - ultrastructure Animals Bacterial Adhesion - physiology Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - metabolism Cells, Cultured Complement Factor H - metabolism Cytokines - genetics Cytokines - metabolism Escherichia coli Escherichia coli - metabolism Escherichia coli - ultrastructure Female Humans Macrophages - immunology Macrophages - metabolism Mice Mice, Inbred BALB C Mutation Omp100 protein Periodontal Diseases - microbiology Recombinant Proteins - genetics Recombinant Proteins - metabolism virulence factors Virulence Factors - genetics Virulence Factors - metabolism
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