New classes of antibacterial oxazolidinones with C-5, methylene O-Linked heterocyclic side chains

Exploration of the structure–activity relationships of the traditional C-5 acetamidomethyl side chain of the oxazolidonone antibacterials has yielded new, potent series of compounds of which the first examples, the O-linked iosoxazoles are described in detail, leading to the selection of the pre-cli...

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