BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis

Thymocyte development is a non–cell-autonomous process that requires signals provided by the thymic stroma. Bone morphogenetic proteins (BMPs) and fibroblast growth factors (FGFs) derived from thymic stroma have been implicated as possible regulators of T-cell development. Using thymic organ culture...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 2003-12, Vol.102 (12), p.3947-3953
Hauptverfasser:	Tsai, Peter T., Lee, Robert A., Wu, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - physiology Cell differentiation, maturation, development, hematopoiesis Cell physiology Chemokines - biosynthesis DNA-Binding Proteins - biosynthesis Fibroblast Growth Factor 10 Fibroblast Growth Factor 7 Fibroblast Growth Factors - physiology Forkhead Transcription Factors Fundamental and applied biological sciences. Psychology Lymphopoiesis Mice Molecular and cellular biology Receptor Protein-Tyrosine Kinases - biosynthesis Receptor, Fibroblast Growth Factor, Type 2 Receptors, Fibroblast Growth Factor - biosynthesis Stromal Cells - cytology Stromal Cells - metabolism T-Lymphocytes - cytology Thymus Gland - cytology Thymus Gland - metabolism Transcription Factors - biosynthesis Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!