Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation

It has been suggested that endothelial apoptosis is a primary lesion in the pathogenesis of thrombotic thrombocytopenic purpura (TTP). We tested this hypothesis by examining the phenotypic signatures of endothelial microparticles (EMP) in TTP patients. In addition, the effect of TTP plasma on microv...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 2003-12, Vol.123 (5), p.896-902
Hauptverfasser:	Jimenez, Joaquin J., Jy, Wenche, Mauro, Lucia M., Horstman, Lawrence L., Soderland, Carl, Ahn, Yeon S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Biomarkers - analysis Case-Control Studies Cells, Cultured E-Selectin - analysis endothelial cell activation Endothelial Cells - chemistry endothelial microparticles endothelium Endothelium, Vascular - pathology Flow Cytometry Hematologic and hematopoietic diseases Hematology Humans Medical sciences Platelet diseases and coagulopathies Platelet Endothelial Cell Adhesion Molecule-1 - analysis Platelet Glycoprotein GPIb-IX Complex - analysis Purpura, Thrombotic Thrombocytopenic - immunology Purpura, Thrombotic Thrombocytopenic - metabolism Purpura, Thrombotic Thrombocytopenic - pathology Statistics, Nonparametric thrombotic thrombocytopenic purpura von Willebrand factor von Willebrand Factor - analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!