Identification of a novel adrenomedullin gene family in teleost fish

Adrenomedullin (AM) is a multifunctional peptide known to form a hormone family with calcitonin gene-related peptide (CGRP) and amylin. We have cloned five distinct AM cDNAs from the pufferfish, Takifugu rubripes, and named them TrAM-1, -2, -3, -4, and -5. Judging from the deduced precursor sequence...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-11, Vol.311 (4), p.1072-1077
Hauptverfasser:	Ogoshi, Maho, Inoue, Koji, Takei, Yoshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin Amino Acid Sequence Animals Cloning, Molecular Comparative genomics Conserved Sequence Danio rerio Evolution, Molecular Fishes - genetics Fishes - metabolism Freshwater Gene Expression Profiling - methods Gene Expression Regulation - physiology Molecular evolution Molecular Sequence Data Peptides - classification Peptides - genetics Peptides - metabolism Pufferfish Sequence Homology Species Specificity Takifugu - genetics Takifugu - metabolism Takifugu rubripes Teleostei Tetraodon nigroviridis Tissue Distribution Vertebrates - genetics Vertebrates - metabolism
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