RET activation and clinicopathologic features in poorly differentiated thyroid tumors

Poorly differentiated carcinoma of the thyroid gland (PDC) represents an heterogeneous group of epithelial neoplasms with morphologic features and clinical characteristics intermediate between well differentiated and anaplastic (undifferentiated) carcinomas. Unlike well differentiated tumors, PDCs a...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2002, Vol.87 (1), p.370-379
Hauptverfasser:	SANTORO, Massimo, PAPOTTI, Mauro, CARCANGIU, Maria Luisa, FUSCO, Alfredo, TALLINI, Giovanni, CHIAPPETTA, Gennaro, GARCIA-ROSTAN, Ginesa, VOLANTE, Marco, JOHNSON, Chaline, CAMP, Robert L, PENTIMALLI, Francesca, MONACO, Carmen, HERRERO, Agustin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Papillary - metabolism Carcinoma, Papillary - pathology Cell Differentiation Drosophila Proteins Endocrinopathies Female Gene Rearrangement Humans Immunohistochemistry Lymphatic Metastasis Male Malignant tumors Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Prognosis Protein-Tyrosine Kinases Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism Reverse Transcriptase Polymerase Chain Reaction Survival Analysis Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Thyroid. Thyroid axis (diseases)
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