AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression

AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression. Excess advanced glycation end-products (AGEs) are formed during renal failure, and AGE formation also may be connected with the high glucose concentration of peritoneal dialysis (PD) fluids. To determine the effect of human per...

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Veröffentlicht in:	Kidney international 2002-01, Vol.61 (1), p.148-156
Hauptverfasser:	Boulanger, Eric, Wautier, Marie-Paule, Wautier, Jean-Luc, Boval, Bernadette, Panis, Yves, Wernert, Nicolas, Danze, Pierre-Marie, Dequiedt, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult advanced glycation end products Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cell Adhesion - immunology Cells, Cultured Emergency and intensive care: renal failure. Dialysis management Female Flow Cytometry Gene Expression - physiology glycation Glycation End Products, Advanced - metabolism Humans inflammation Intensive care medicine Intercellular Adhesion Molecule-1 - genetics Intercellular Adhesion Molecule-1 - metabolism Kidney Diseases - metabolism Kidney Diseases - therapy leukocytes Leukocytes - metabolism Male Medical sciences Middle Aged Peritoneal Dialysis Peritoneum - cytology Peritoneum - metabolism Receptor for Advanced Glycation End Products Receptors, Immunologic - genetics Receptors, Immunologic - metabolism RNA, Messenger - analysis Umbilical Veins - cytology Vascular Cell Adhesion Molecule-1 - genetics Vascular Cell Adhesion Molecule-1 - metabolism
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