Chronic actinic dermatitis: A retrospective analysis of 44 cases referred to an Australian photobiology clinic

SUMMARY A retrospective study was performed to analyse the clinical and photobiological features and therapeutic outcomes of 44 patients with chronic actinic dermatitis who were evaluated over an 8.3‐year period. The study population comprised 37 men and seven women with a mean age of 62.7 years (ra...

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Veröffentlicht in:Australasian journal of dermatology 2003-11, Vol.44 (4), p.256-262
Hauptverfasser: Yap, Lee Mei, Foley, Peter, Crouch, Rohan, Baker, Christopher
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container_title Australasian journal of dermatology
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creator Yap, Lee Mei
Foley, Peter
Crouch, Rohan
Baker, Christopher
description SUMMARY A retrospective study was performed to analyse the clinical and photobiological features and therapeutic outcomes of 44 patients with chronic actinic dermatitis who were evaluated over an 8.3‐year period. The study population comprised 37 men and seven women with a mean age of 62.7 years (range 26–85 years). The most common abnormal phototest results were decreased minimal erythema doses to both UVA and ‐B (73.8%), and to UVA alone (14.3%). Twenty‐six patients (78.8%) had at least one allergic, photoallergic or combined allergic/photoallergic reaction. A total of 139 positive contact or photocontact reactions were recorded (mean 4.2 per patient). Most commonly, treatment consisted of photoprotection, topical corticosteroids and episodic use of systemic agents, in particular azathioprine.
doi_str_mv 10.1046/j.1440-0960.2003.00004.x
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The study population comprised 37 men and seven women with a mean age of 62.7 years (range 26–85 years). The most common abnormal phototest results were decreased minimal erythema doses to both UVA and ‐B (73.8%), and to UVA alone (14.3%). Twenty‐six patients (78.8%) had at least one allergic, photoallergic or combined allergic/photoallergic reaction. A total of 139 positive contact or photocontact reactions were recorded (mean 4.2 per patient). Most commonly, treatment consisted of photoprotection, topical corticosteroids and episodic use of systemic agents, in particular azathioprine.</description><identifier>ISSN: 0004-8380</identifier><identifier>EISSN: 1440-0960</identifier><identifier>DOI: 10.1046/j.1440-0960.2003.00004.x</identifier><identifier>PMID: 14616491</identifier><identifier>CODEN: AJDEBP</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Pty</publisher><subject>actinic reticuloid ; Adrenal Cortex Hormones - therapeutic use ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Ambulatory Care Facilities ; azathioprine ; Biological and medical sciences ; Biopsy, Needle ; Cohort Studies ; Dermatology ; Female ; Humans ; Immunohistochemistry ; Immunosuppressive Agents - therapeutic use ; Incidence ; Injuries of the skin. Diseases of the skin due to physical agents ; Male ; Medical sciences ; Middle Aged ; Patch Tests ; persistent light reactivity ; photopatch testing ; photosensitivity dermatitis ; photosensitivity disorders ; Photosensitivity Disorders - diagnosis ; Photosensitivity Disorders - epidemiology ; Photosensitivity Disorders - therapy ; phototesting ; Phototherapy - methods ; Prognosis ; Referral and Consultation ; Retrospective Studies ; Risk Assessment ; Severity of Illness Index ; Sex Distribution ; Skin involvement in other diseases. Miscellaneous. General aspects ; sunlight ; Traumas. 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The study population comprised 37 men and seven women with a mean age of 62.7 years (range 26–85 years). The most common abnormal phototest results were decreased minimal erythema doses to both UVA and ‐B (73.8%), and to UVA alone (14.3%). Twenty‐six patients (78.8%) had at least one allergic, photoallergic or combined allergic/photoallergic reaction. A total of 139 positive contact or photocontact reactions were recorded (mean 4.2 per patient). Most commonly, treatment consisted of photoprotection, topical corticosteroids and episodic use of systemic agents, in particular azathioprine.</description><subject>actinic reticuloid</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Ambulatory Care Facilities</subject><subject>azathioprine</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Cohort Studies</subject><subject>Dermatology</subject><subject>Female</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Incidence</subject><subject>Injuries of the skin. Diseases of the skin due to physical agents</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Patch Tests</subject><subject>persistent light reactivity</subject><subject>photopatch testing</subject><subject>photosensitivity dermatitis</subject><subject>photosensitivity disorders</subject><subject>Photosensitivity Disorders - diagnosis</subject><subject>Photosensitivity Disorders - epidemiology</subject><subject>Photosensitivity Disorders - therapy</subject><subject>phototesting</subject><subject>Phototherapy - methods</subject><subject>Prognosis</subject><subject>Referral and Consultation</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><subject>sunlight</subject><subject>Traumas. Diseases due to physical agents</subject><subject>Treatment Outcome</subject><subject>Victoria - epidemiology</subject><issn>0004-8380</issn><issn>1440-0960</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMGO0zAQhi0EYsvCKyBf4JYwUztOgrhUhe2CKhACxN4s156wLmld7BTat8eh1e6VkawZeb5_7PkZ4wglglSv1iVKCQW0CsopgCghhywPD9jkrvGQTcbLohENXLAnKa0BUGBVPWYXKBUq2eKEbee3MWy95cYOfsyO4sYMfvDpNZ_xSEMMaUe5-Zu42Zr-mHzioeNScmsSpYx0FCM5PoQM8Nk-DdH0Ppe72zCElQ99-HHkth_HP2WPOtMnenbOl-zb1buv8-ti-Wnxfj5bFlbIWhZUAa7A2UY4h0SixmnTKBCdQ9W0nZ1WplUVOKny9uDQIVQ5VtTm09FUXLKXp7m7GH7tKQ1645OlvjdbCvukaxQqT8IMNifQ5j1T3kXvot-YeNQIevRar_VoqR4t1aPX-p_X-pClz89v7FcbcvfCs7kZeHEGTLKm76LZWp_uuUogINaZe3Pi_viejv_9AT378DYXWV6c5D4NdLiTm_hTq1rUlf7-caGXn9XV4ubmWn8RfwHyialL</recordid><startdate>200311</startdate><enddate>200311</enddate><creator>Yap, Lee Mei</creator><creator>Foley, Peter</creator><creator>Crouch, Rohan</creator><creator>Baker, Christopher</creator><general>Blackwell Science Pty</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200311</creationdate><title>Chronic actinic dermatitis: A retrospective analysis of 44 cases referred to an Australian photobiology clinic</title><author>Yap, Lee Mei ; Foley, Peter ; Crouch, Rohan ; Baker, Christopher</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3474-e501b0dc83dd1ee371288603fd1689fc25a9650d462000d1d105555be95befe23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>actinic reticuloid</topic><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Ambulatory Care Facilities</topic><topic>azathioprine</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Cohort Studies</topic><topic>Dermatology</topic><topic>Female</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Incidence</topic><topic>Injuries of the skin. Diseases of the skin due to physical agents</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Patch Tests</topic><topic>persistent light reactivity</topic><topic>photopatch testing</topic><topic>photosensitivity dermatitis</topic><topic>photosensitivity disorders</topic><topic>Photosensitivity Disorders - diagnosis</topic><topic>Photosensitivity Disorders - epidemiology</topic><topic>Photosensitivity Disorders - therapy</topic><topic>phototesting</topic><topic>Phototherapy - methods</topic><topic>Prognosis</topic><topic>Referral and Consultation</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><topic>sunlight</topic><topic>Traumas. Diseases due to physical agents</topic><topic>Treatment Outcome</topic><topic>Victoria - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yap, Lee Mei</creatorcontrib><creatorcontrib>Foley, Peter</creatorcontrib><creatorcontrib>Crouch, Rohan</creatorcontrib><creatorcontrib>Baker, Christopher</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Australasian journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yap, Lee Mei</au><au>Foley, Peter</au><au>Crouch, Rohan</au><au>Baker, Christopher</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic actinic dermatitis: A retrospective analysis of 44 cases referred to an Australian photobiology clinic</atitle><jtitle>Australasian journal of dermatology</jtitle><addtitle>Australas J Dermatol</addtitle><date>2003-11</date><risdate>2003</risdate><volume>44</volume><issue>4</issue><spage>256</spage><epage>262</epage><pages>256-262</pages><issn>0004-8380</issn><eissn>1440-0960</eissn><coden>AJDEBP</coden><abstract>SUMMARY A retrospective study was performed to analyse the clinical and photobiological features and therapeutic outcomes of 44 patients with chronic actinic dermatitis who were evaluated over an 8.3‐year period. The study population comprised 37 men and seven women with a mean age of 62.7 years (range 26–85 years). The most common abnormal phototest results were decreased minimal erythema doses to both UVA and ‐B (73.8%), and to UVA alone (14.3%). Twenty‐six patients (78.8%) had at least one allergic, photoallergic or combined allergic/photoallergic reaction. A total of 139 positive contact or photocontact reactions were recorded (mean 4.2 per patient). Most commonly, treatment consisted of photoprotection, topical corticosteroids and episodic use of systemic agents, in particular azathioprine.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Pty</pub><pmid>14616491</pmid><doi>10.1046/j.1440-0960.2003.00004.x</doi><tpages>7</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects actinic reticuloid
Adrenal Cortex Hormones - therapeutic use
Adult
Age Distribution
Aged
Aged, 80 and over
Ambulatory Care Facilities
azathioprine
Biological and medical sciences
Biopsy, Needle
Cohort Studies
Dermatology
Female
Humans
Immunohistochemistry
Immunosuppressive Agents - therapeutic use
Incidence
Injuries of the skin. Diseases of the skin due to physical agents
Male
Medical sciences
Middle Aged
Patch Tests
persistent light reactivity
photopatch testing
photosensitivity dermatitis
photosensitivity disorders
Photosensitivity Disorders - diagnosis
Photosensitivity Disorders - epidemiology
Photosensitivity Disorders - therapy
phototesting
Phototherapy - methods
Prognosis
Referral and Consultation
Retrospective Studies
Risk Assessment
Severity of Illness Index
Sex Distribution
Skin involvement in other diseases. Miscellaneous. General aspects
sunlight
Traumas. Diseases due to physical agents
Treatment Outcome
Victoria - epidemiology
title Chronic actinic dermatitis: A retrospective analysis of 44 cases referred to an Australian photobiology clinic
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