Escherichia coli Harboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical Symptoms

Shiga toxin (Stx)–producing Escherichia coli (STEC) from patients with hemolytic-uremic syndrome (HUS), patients with diarrhea without HUS, or asymptomatic subjects were genotyped to assess associations between stx2 variants and clinical manifestations of infection. Neither stx2d nor stx2e was found...

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Veröffentlicht in:	The Journal of infectious diseases 2002-01, Vol.185 (1), p.74-84
Hauptverfasser:	Friedrich, Alexander W., Bielaszewska, Martina, Zhang, Wen-Lan, Pulz, Matthias, Kuczius, Thorsten, Ammon, Andrea, Karch, Helge
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - genetics Agglutination Bacteriology Biological and medical sciences Carrier Proteins - genetics Diarrhea Diarrhea - microbiology Epidemiology Escherichia coli Escherichia coli - genetics Escherichia coli Infections - microbiology Escherichia coli O157 Escherichia coli O157 - isolation & purification Escherichia coli Proteins Feces - microbiology Fundamental and applied biological sciences. Psychology Genetic Variation Genotype Genotypes Hemolytic uremic syndrome Hemolytic-Uremic Syndrome - microbiology Humans Infections Latex Major Articles Microbiology O Antigens Serotyping Shiga toxin 2 Shiga Toxin 2 - genetics Shiga toxins stx2c gene stx2d gene stx2e gene stx2f gene Toxins
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Zusammenfassung:	Shiga toxin (Stx)–producing Escherichia coli (STEC) from patients with hemolytic-uremic syndrome (HUS), patients with diarrhea without HUS, or asymptomatic subjects were genotyped to assess associations between stx2 variants and clinical manifestations of infection. Neither stx2d nor stx2e was found in 268 STEC isolates from patients with HUS. Of 262 STEC isolates from patients with diarrhea, stx2d was found in 41 (15.6%; P
ISSN:	0022-1899 1537-6613
DOI:	10.1086/338115