The B-cell transcription factors BSAP, Oct-2, and BOB.1 and the Pan-B-cell markers CD20, CD22, and CD79a are useful in the differential diagnosis of classic Hodgkin lymphoma

Even with routine immunohistochemical evaluation, distinguishing classic Hodgkin lymphoma (CHL) from diffuse large B-cell lymphoma (DLBCL) or anaplastic large cell lymphoma (ALCL) can be difficult. In these cases, the transcription factors (B cell-specific activator protein [BSAP], octamer-binding t...

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Veröffentlicht in:	American journal of clinical pathology 2003-11, Vol.120 (5), p.767-777
Hauptverfasser:	BROWNE, Patrick, PETROSYAN, Karen, HERNANDEZ, Antonio, CHAN, Joel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - analysis Antigens, CD20 - analysis Antigens, Differentiation, B-Lymphocyte - analysis Biological and medical sciences CD79 Antigens Cell Adhesion Molecules Diagnosis, Differential DNA-Binding Proteins - analysis Hematologic and hematopoietic diseases Hodgkin Disease - diagnosis Hodgkin Disease - immunology Humans Immunohistochemistry Lectins - analysis Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoid Tissue - chemistry Lymphoma, B-Cell - diagnosis Lymphoma, Large B-Cell, Diffuse - diagnosis Medical sciences Octamer Transcription Factor-2 PAX5 Transcription Factor Receptors, Antigen, B-Cell - analysis Sialic Acid Binding Ig-like Lectin 2 Trans-Activators - analysis Transcription Factors - analysis
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