Colony-stimulating activity of fetal liver cells: synergistic role of stem cell factor in bone marrow recovery from aplastic anemia

Previously, we and others have shown that fetal liver infusion (FLI) leads to autologous hematopoietic improvement in 40-54% of patients with aplastic anemia. However, whether this recovery was spontaneous or the effect of the infused liver cells was not clear. To dissect the role of FLI in autologo...

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Veröffentlicht in:	Journal of hematotherapy & stem cell research 2003-10, Vol.12 (5), p.491-497
Hauptverfasser:	Raju, G M K, Guha, S, Mukhopadhyay, A, Kumar, L, Kale, V P, Mittal, S, Deka, D, Mohanty, S, Kochupillai, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Aplastic - blood Anemia, Aplastic - drug therapy Antibodies, Monoclonal - pharmacology Bone Marrow Cells - drug effects Cells, Cultured Colony-Forming Units Assay Colony-Stimulating Factors - pharmacology Colony-Stimulating Factors - physiology Culture Media, Conditioned - chemistry Culture Media, Conditioned - pharmacology Enzyme-Linked Immunosorbent Assay Erythropoietin - analysis Female Fetus Granulocyte-Macrophage Colony-Stimulating Factor - analysis Hematopoietic Stem Cells - metabolism Hematopoietic Stem Cells - secretion Hepatocytes - chemistry Hepatocytes - secretion Humans Interleukin-3 - analysis Pregnancy Stem Cell Factor - analysis Stem Cell Factor - immunology Stem Cell Factor - physiology
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