Roles of 5‐substituents of tRNA wobble uridines in the recognition of purine‐ending codons

Many tRNA molecules that recognize the purine‐ending codons but not the pyrimidine‐ending codons have a modified uridine at the wobble position, in which a methylene carbon is attached directly to position 5 of the uracil ring. Although several models have been proposed concerning the mechanism by w...

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Veröffentlicht in:	Nucleic acids research 2003-11, Vol.31 (22), p.6383-6391
Hauptverfasser:	Takai, Kazuyuki, Yokoyama, Shigeyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticodon - chemistry Anticodon - genetics Codon - chemistry Codon - genetics Models, Genetic Protein Biosynthesis Purine Nucleotides - chemistry Purine Nucleotides - genetics RNA, Transfer - chemistry RNA, Transfer - genetics Thermodynamics Uridine - chemistry Uridine - genetics
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