A Transgenic Lef1/β-Catenin-Dependent Reporter Is Expressed in Spatially Restricted Domains throughout Zebrafish Development

The Wnt/β-catenin signaling pathway plays multiple roles during embryonic development, only a few of which have been extensively characterized. Although domains of Wnt expression have been identified throughout embryogenesis, anatomical and molecular characterization of responding cells has been mos...

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Veröffentlicht in:	Developmental biology 2002-01, Vol.241 (2), p.229-237
Hauptverfasser:	Dorsky, Richard I., Sheldahl, Laird C., Moon, Randall T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified beta Catenin Binding Sites Body Patterning - genetics Brain - embryology Brain - metabolism Cytoskeletal Proteins - genetics Cytoskeletal Proteins - physiology DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Embryo, Nonmammalian - metabolism Embryo, Nonmammalian - ultrastructure Gene Expression Regulation, Developmental Genes, fos Genes, Reporter Genes, Synthetic GFP Green Fluorescent Proteins HMGB Proteins - genetics HMGB Proteins - physiology Lef1 Luminescent Proteins - biosynthesis Luminescent Proteins - genetics Lymphoid Enhancer-Binding Factor 1 Microinjections Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - genetics Oligodeoxyribonucleotides, Antisense - pharmacology Pigment Epithelium of Eye - embryology Pigment Epithelium of Eye - metabolism Promoter Regions, Genetic Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Recombinant Fusion Proteins - biosynthesis reporter Tail - embryology Tail - metabolism TCF Transcription Factors Tcf3 Trans-Activators Transcription Factor 7-Like 1 Protein Transcription Factors - genetics Transcription Factors - physiology Transcription, Genetic transgenic Wnt Wnt Proteins Wnt1 Protein zebrafish Zebrafish - embryology Zebrafish Proteins Zygote - metabolism Zygote - ultrastructure β-catenin
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