Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea
Electrophysiological recordings from taste sensilla of the caterpillar Estigmene acrea with the pyrrolizidine alkaloid (PA) seneciphylline N-oxide demonstrated that extensive feeding on plants rich in PAs caused a loss in response of the PA-sensitive cell in the lateral styloconic sensillum on the g...
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| Veröffentlicht in: | Journal of experimental biology 2003-12, Vol.206 (Pt 24), p.4487-4496 |
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| container_end_page | 4496 |
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| container_issue | Pt 24 |
| container_start_page | 4487 |
| container_title | Journal of experimental biology |
| container_volume | 206 |
| creator | Bernays, E A Rodrigues, D Chapman, R F Singer, M S Hartmann, T |
| description | Electrophysiological recordings from taste sensilla of the caterpillar Estigmene acrea with the pyrrolizidine alkaloid (PA) seneciphylline N-oxide demonstrated that extensive feeding on plants rich in PAs caused a loss in response of the PA-sensitive cell in the lateral styloconic sensillum on the galea. The effect could be repeated using pure PAs fed to the insect in synthetic diets and by injection of PA into the hemolymph. The sensitivity loss lasted for approximately two hours and was less pronounced in individuals that had been reared on PA-containing food. Behavioral experiments and field observations demonstrate a parallel reduction in responsiveness to PAs and to PA-containing plants. |
| doi_str_mv | 10.1242/jeb.00705 |
| format | Article |
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The effect could be repeated using pure PAs fed to the insect in synthetic diets and by injection of PA into the hemolymph. The sensitivity loss lasted for approximately two hours and was less pronounced in individuals that had been reared on PA-containing food. Behavioral experiments and field observations demonstrate a parallel reduction in responsiveness to PAs and to PA-containing plants.</description><identifier>ISSN: 0022-0949</identifier><identifier>EISSN: 1477-9145</identifier><identifier>DOI: 10.1242/jeb.00705</identifier><identifier>PMID: 14610033</identifier><language>eng</language><publisher>England</publisher><subject>Animals ; Arctiidae ; Arizona ; Chemoreceptor Cells - metabolism ; Chemoreceptor Cells - physiology ; Diet ; Eating - drug effects ; Eating - physiology ; Electrophysiology ; Estigmene acrea ; Hemolymph - metabolism ; Larva - physiology ; Moths - physiology ; Pyrrolizidine Alkaloids - blood ; Pyrrolizidine Alkaloids - metabolism ; Pyrrolizidine Alkaloids - pharmacology</subject><ispartof>Journal of experimental biology, 2003-12, Vol.206 (Pt 24), p.4487-4496</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-6fa7d938d28e3ed90a2b02a3e8d8c0a1d30c54d43f6140e2c736d2ae30b0ceb43</citedby><cites>FETCH-LOGICAL-c350t-6fa7d938d28e3ed90a2b02a3e8d8c0a1d30c54d43f6140e2c736d2ae30b0ceb43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3664,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14610033$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bernays, E A</creatorcontrib><creatorcontrib>Rodrigues, D</creatorcontrib><creatorcontrib>Chapman, R F</creatorcontrib><creatorcontrib>Singer, M S</creatorcontrib><creatorcontrib>Hartmann, T</creatorcontrib><title>Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea</title><title>Journal of experimental biology</title><addtitle>J Exp Biol</addtitle><description>Electrophysiological recordings from taste sensilla of the caterpillar Estigmene acrea with the pyrrolizidine alkaloid (PA) seneciphylline N-oxide demonstrated that extensive feeding on plants rich in PAs caused a loss in response of the PA-sensitive cell in the lateral styloconic sensillum on the galea. The effect could be repeated using pure PAs fed to the insect in synthetic diets and by injection of PA into the hemolymph. The sensitivity loss lasted for approximately two hours and was less pronounced in individuals that had been reared on PA-containing food. Behavioral experiments and field observations demonstrate a parallel reduction in responsiveness to PAs and to PA-containing plants.</description><subject>Animals</subject><subject>Arctiidae</subject><subject>Arizona</subject><subject>Chemoreceptor Cells - metabolism</subject><subject>Chemoreceptor Cells - physiology</subject><subject>Diet</subject><subject>Eating - drug effects</subject><subject>Eating - physiology</subject><subject>Electrophysiology</subject><subject>Estigmene acrea</subject><subject>Hemolymph - metabolism</subject><subject>Larva - physiology</subject><subject>Moths - physiology</subject><subject>Pyrrolizidine Alkaloids - blood</subject><subject>Pyrrolizidine Alkaloids - metabolism</subject><subject>Pyrrolizidine Alkaloids - pharmacology</subject><issn>0022-0949</issn><issn>1477-9145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctLAzEQxoMotj4O_gOSk-Bh6-Sxr6MUX1Dwouclm8y2qdvNmmzFevf_NrUFj85lBuY3Hx_zEXLBYMK45DdLrCcAOaQHZMxkniclk-khGQNwnkApyxE5CWEJsbJUHpMRkxkDEGJMvmcuBOoaOl-HQQ3Ob6jH0LsuYKCDo_3Ge9faL2tsh1S1b6p11gSqmgE9HRZoPcXPAbtgP5Dabo5hsK6L03ZJe9du-oWau3WgWsWT3rat8vQuUvMVbiW1R3VGjhrVBjzf91Pyen_3Mn1MZs8PT9PbWaJFCkOSNSo3pSgML1CgKUHxGrgSWJhCg2JGgE6lkaLJmATkOheZ4QoF1KCxluKUXO10e-_e19FqtbJBY7TUYbRY5UykmSjZvyDLizIrCojg9Q7UPj7SY1P13q6U31QMqm04VQyn-g0nspd70XW9QvNH7tMQP3dojhQ</recordid><startdate>20031201</startdate><enddate>20031201</enddate><creator>Bernays, E A</creator><creator>Rodrigues, D</creator><creator>Chapman, R F</creator><creator>Singer, M S</creator><creator>Hartmann, T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7SS</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20031201</creationdate><title>Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea</title><author>Bernays, E A ; Rodrigues, D ; Chapman, R F ; Singer, M S ; Hartmann, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-6fa7d938d28e3ed90a2b02a3e8d8c0a1d30c54d43f6140e2c736d2ae30b0ceb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Animals</topic><topic>Arctiidae</topic><topic>Arizona</topic><topic>Chemoreceptor Cells - metabolism</topic><topic>Chemoreceptor Cells - physiology</topic><topic>Diet</topic><topic>Eating - drug effects</topic><topic>Eating - physiology</topic><topic>Electrophysiology</topic><topic>Estigmene acrea</topic><topic>Hemolymph - metabolism</topic><topic>Larva - physiology</topic><topic>Moths - physiology</topic><topic>Pyrrolizidine Alkaloids - blood</topic><topic>Pyrrolizidine Alkaloids - metabolism</topic><topic>Pyrrolizidine Alkaloids - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bernays, E A</creatorcontrib><creatorcontrib>Rodrigues, D</creatorcontrib><creatorcontrib>Chapman, R F</creatorcontrib><creatorcontrib>Singer, M S</creatorcontrib><creatorcontrib>Hartmann, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of experimental biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bernays, E A</au><au>Rodrigues, D</au><au>Chapman, R F</au><au>Singer, M S</au><au>Hartmann, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea</atitle><jtitle>Journal of experimental biology</jtitle><addtitle>J Exp Biol</addtitle><date>2003-12-01</date><risdate>2003</risdate><volume>206</volume><issue>Pt 24</issue><spage>4487</spage><epage>4496</epage><pages>4487-4496</pages><issn>0022-0949</issn><eissn>1477-9145</eissn><abstract>Electrophysiological recordings from taste sensilla of the caterpillar Estigmene acrea with the pyrrolizidine alkaloid (PA) seneciphylline N-oxide demonstrated that extensive feeding on plants rich in PAs caused a loss in response of the PA-sensitive cell in the lateral styloconic sensillum on the galea. 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| ispartof | Journal of experimental biology, 2003-12, Vol.206 (Pt 24), p.4487-4496 |
| issn | 0022-0949 1477-9145 |
| language | eng |
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| source | MEDLINE; EZB Electronic Journals Library; Company of Biologists |
| subjects | Animals Arctiidae Arizona Chemoreceptor Cells - metabolism Chemoreceptor Cells - physiology Diet Eating - drug effects Eating - physiology Electrophysiology Estigmene acrea Hemolymph - metabolism Larva - physiology Moths - physiology Pyrrolizidine Alkaloids - blood Pyrrolizidine Alkaloids - metabolism Pyrrolizidine Alkaloids - pharmacology |
| title | Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea |
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