Ex vivo expansion of limbal epithelial stem cells: amniotic membrane serving as a stem cell niche

Identification, maintenance, and expansion of stem cells for subsequent transplantation has become a new strategy for treating many diseases in most medical subspecialties. The stem cells of the corneal epithelium are located in the limbal basal layer and are the ultimate source for constant corneal...

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Veröffentlicht in:	Survey of ophthalmology 2003-11, Vol.48 (6), p.631-646
Hauptverfasser:	Grueterich, Martin, Espana, Edgar M., Tseng, Scheffer C.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	allograft Amnion amniotic membrane autograft Biological and medical sciences Biomarkers - analysis Cell Culture Techniques - methods Cell Differentiation Cell Division Corneal Diseases - surgery differentiation Epithelial Cells - cytology Epithelial Cells - physiology epithelium Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Humans limbal stem cell deficiency limbus Limbus Corneae - cytology Medical sciences stem cell Stem Cell Transplantation Stem Cells - cytology Stem Cells - physiology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit Vertebrates: nervous system and sense organs
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