Enantioselective determination of felodipine in human plasma by chiral normal-phase liquid chromatography and electrospray ionisation mass spectrometry

An analytical method was developed for the determination of the enantiomers of felodipine, a dihydropyridine-type calcium antagonist, in human blood plasma. Felodipine was extracted from plasma using toluene as extraction solvent. The enantiomers were separated on a cellulose tris(4-methyl benzoate)...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2002-01, Vol.27 (3), p.489-495
Hauptverfasser:	Lindmark, Bo, Ahnoff, Martin, Persson, Bengt-Arne
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Channel Blockers - blood Calcium Channel Blockers - chemistry Chiral normal-phase LC–MS Chromatography, Liquid - methods Enantioselective determination of felodipine felodipine Felodipine - blood Felodipine - chemistry Felodipine enantiomers in plasma Humans Spectrometry, Mass, Electrospray Ionization - methods Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!