Programmable microchip monitoring of post-stroke pyrexia: effects of aspirin and paracetamol on temperature and infarct size in the rat

Background: Recent studies have demonstrated spontaneous and prolonged hyperthermia following stroke in both humans and rodents. However, a full characterization of these pyretic changes and the effects of anti-pyretic drugs on outcome is not available. Methods: The aims of this study were to monito...

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Veröffentlicht in:	Journal of neuroscience methods 2002-01, Vol.113 (2), p.159-166
Hauptverfasser:	Legos, Jeffrey J, Mangoni, Arduino A, Read, Simon J, Campbell, Colin A, Irving, Elaine A, Roberts, Jenny, Barone, Frank C, Parsons, Andrew A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - pharmacology Analgesics, Non-Narcotic - pharmacology Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Antipyretic Aspirin - pharmacology Biological and medical sciences Body temperature Body Temperature - drug effects Fever - drug therapy Fever - pathology Fever - physiopathology Focal ischemia Fundamental and applied biological sciences. Psychology General aspects. Models. Methods Hyperthermia Hypothalamus Hypothalamus - pathology Hypothalamus - physiopathology Infarction, Middle Cerebral Artery - drug therapy Infarction, Middle Cerebral Artery - pathology Infarction, Middle Cerebral Artery - physiopathology Male Programmable microchips Rats Rats, Sprague-Dawley Software Telemetry - instrumentation Telemetry recording Vertebrates: nervous system and sense organs
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