Light-induced changes in glutamate release from isolated rat retina is regulated by cyclic guanosine monophosphate

Isolated rat retina was preloaded with [14C]glutamate and subsequently superfused to follow release of glutamate (Glu). After 20 min of superfusion in the dark, exposure of the [14C]Glu preloaded rat retina to a single train of white light pulses reduced Glu efflux significantly in the absence as we...

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Veröffentlicht in:	Journal of neuroscience research 2002-01, Vol.67 (2), p.149-155
Hauptverfasser:	Barabás, Péter, Kovács, Ilona, Kovács, Richárd, Pálhalmi, János, Kardos, Julianna, Schousboe, Arne
Format:	Artikel
Sprache:	eng
Schlagworte:	4-dicarboxylate LY83583 [14C]Glu efflux Aminoquinolines - pharmacology Animals Carbon Radioisotopes - pharmacokinetics Cyclic GMP - metabolism Dark Adaptation - drug effects Dark Adaptation - physiology Dicarboxylic Acids - pharmacology Enzyme Inhibitors - pharmacology Glutamic Acid - metabolism Glutamic Acid - pharmacokinetics Male Neurons - drug effects Neurons - metabolism Neurotransmitter Uptake Inhibitors - pharmacology Organ Culture Techniques Phosphodiesterase Inhibitors - pharmacology Photic Stimulation photoresponse Purinones - pharmacology Pyrrolidines - pharmacology rat retina Rats Rats, Long-Evans Retina - drug effects Retina - metabolism Synaptic Transmission - drug effects Synaptic Transmission - physiology trans-L-pyrrolidine-2 trans‐L‐pyrrolidine‐2,4‐dicarboxylate LY83583 Vision, Ocular - drug effects Vision, Ocular - physiology Zaprinast
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