Expression and localization of AT1 receptors in hepatic Kupffer cells: its potential role in regulating a fibrogenic response

Previous studies have showed that the renin-angiotensin system (RAS) plays an important role in the pathogenesis of liver cirrhosis. The localization of angiotensin II receptor in hepatic stellate cells opens up a new research direction of RAS in the regulation of liver fibrosis. However, the potent...

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Veröffentlicht in:	Regulatory peptides 2003-11, Vol.116 (1-3), p.61-69
Hauptverfasser:	PO SING LEUNG, PO MAN SUEN, SIU PO IP, CHUN KIT YIP, CHEN, George, LAI, Paul B. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Animals Base Sequence Biological and medical sciences Fibronectins - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Hepatocytes - drug effects Hepatocytes - metabolism Immunohistochemistry Kupffer Cells - drug effects Kupffer Cells - metabolism Male Molecular Sequence Data Rats Rats, Sprague-Dawley Receptors, Angiotensin - analysis Receptors, Angiotensin - genetics Receptors, Angiotensin - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transforming Growth Factor beta - genetics Vertebrates: endocrinology
Online-Zugang:	Volltext
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