Heterotachy, an important process of protein evolution

Because of functional constraints, substitution rates vary among the positions of a protein but are usually assumed to be constant at a given site during evolution. The distribution of the rates across the sequence positions generally fits a Gamma distribution. Models of sequence evolution were acco...

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Veröffentlicht in:	Molecular biology and evolution 2002-01, Vol.19 (1), p.1-7
Hauptverfasser:	Lopez, P, Casane, D, Philippe, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution Animals Classification Computational Biology Computer Simulation Cytochrome b Group - chemistry Evolution, Molecular Models, Molecular Phylogeny Protein Structure, Secondary Proteins - chemistry Proteins - classification Structure-Activity Relationship
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