The First Applications of Carbene Ligands in Cross-Couplings of Alkyl Electrophiles:  Sonogashira Reactions of Unactivated Alkyl Bromides and Iodides

A Pd/N-heterocyclic carbene-based catalyst achieves the Sonogashira coupling of an array of functionalized, β-hydrogen-containing alkyl bromides and iodides under mild conditions. By furnishing the first example of a nonphosphine-based palladium catalyst for cross-coupling unactivated alkyl electrop...

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Veröffentlicht in:	Journal of the American Chemical Society 2003-11, Vol.125 (45), p.13642-13643
Hauptverfasser:	Eckhardt, Matthias, Fu, Gregory C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemical synthesis Alkynes - chemistry Chemistry Exact sciences and technology Hydrocarbons, Brominated - chemistry Hydrocarbons, Iodinated - chemistry Kinetics and mechanisms Organic chemistry Reactivity and mechanisms
Online-Zugang:	Volltext
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