Contributions from Self-Renewal and Trafficking to the Uterine NK Cell Population of Early Pregnancy

Uterine NK (uNK) cells are abundant in human and murine uteri during decidualization. It is unclear whether precursors of uNK (pre-uNK) cells self-renew or are recruited from other sites. To assess self-renewal of pre-uNK cells, uterine segments from NK cell-competent mice were grafted orthotopicall...

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Veröffentlicht in:	The Journal of immunology (1950) 2002-01, Vol.168 (1), p.22-28
Hauptverfasser:	Chantakru, Sirirak, Miller, Craig, Roach, Lindsay E, Kuziel, William A, Maeda, Nobuyo, Wang, Wan-Chao, Evans, Sharon S, Croy, B. Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Antigens, CD - physiology Bone Marrow Cells - immunology Bone Marrow Transplantation Cell Adhesion Cell Movement decidua DNA-Binding Proteins - genetics Female Integrin alpha4 Interleukin Receptor Common gamma Subunit Killer Cells, Natural - immunology L-Selectin - physiology Lymph Nodes - immunology Lymph Nodes - transplantation Mice Mice, Inbred C57BL Mice, Knockout Mice, SCID Pregnancy - immunology Receptors, Interleukin-7 - genetics Spleen - immunology Spleen - transplantation Stem Cells - immunology Thymus Gland - immunology Thymus Gland - transplantation Uterus - cytology Uterus - immunology Uterus - transplantation
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