Expression of a sodium bicarbonate cotransporter in human parotid salivary glands

The human parotid gland secretes much of the bicarbonate that enters the mouth. Prompted by studies of animal models, this study sought evidence for the expression of a functional Na +–HCO 3 − cotransporter (NBC) in human parotid acinar cells. Microfluorometric measurements of intracellular pH in is...

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Veröffentlicht in:	Archives of oral biology 2002, Vol.47 (1), p.1-9
Hauptverfasser:	Park, K, Hurley, P.T, Roussa, E, Cooper, G.J, Smith, C.P, Thévenod, F, Steward, M.C, Case, R.M
Format:	Artikel
Sprache:	eng
Schlagworte:	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology Adult Aged Amiloride - pharmacology Ammonium Chloride - pharmacology Animals Bicarbonate secretion Cell Membrane - metabolism Cloning, Molecular Cytophotometry Dentistry Diuretics - pharmacology Female Gene Expression Humans Hydrogen-Ion Concentration Immunohistochemistry Intracellular pH Male Membrane Potentials - physiology Microelectrodes Middle Aged NBC Oocytes - metabolism Parotid Gland - cytology Parotid Gland - metabolism Protein Isoforms - antagonists & inhibitors Protein Isoforms - genetics Protein Isoforms - metabolism Sodium - metabolism Sodium - pharmacology Sodium-Bicarbonate Symporters - antagonists & inhibitors Sodium-Bicarbonate Symporters - genetics Sodium-Bicarbonate Symporters - metabolism Sodium-Hydrogen Exchangers - antagonists & inhibitors Sodium-Hydrogen Exchangers - metabolism Statistics as Topic Xenopus laevis
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