Endogenous Sex Hormones and Cardiovascular Disease in Men
Unlike women, men do not experience an abrupt reduction in endogenous sex hormone production. It has, however, become clear that an age-associated decrease in the levels of (bioactive) sex hormones does occur. Whether endogenous sex hormones have an impact on cardiovascular disease has for many year...
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| Veröffentlicht in: | The journal of clinical endocrinology and metabolism 2003-11, Vol.88 (11), p.5076-5086 |
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| container_issue | 11 |
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| container_title | The journal of clinical endocrinology and metabolism |
| container_volume | 88 |
| creator | Muller, Majon van der Schouw, Yvonne T. Thijssen, Jos H. H. Grobbee, Diederick E. |
| description | Unlike women, men do not experience an abrupt reduction in endogenous sex hormone production. It has, however, become clear that an age-associated decrease in the levels of (bioactive) sex hormones does occur. Whether endogenous sex hormones have an impact on cardiovascular disease has for many years remained largely unknown, but during the last decade more attention has been drawn to the importance of testosterone, estrogens, and adrenal androgens in etiology, prevention, and treatment of male cardiovascular disease. The purpose of this article is to summarize the evidence currently available on the association between endogenous sex hormones and cardiovascular disease in males. Published studies dealing with the relationship between circulating levels of sex hormones and cardiovascular disease in males were reviewed. The studies reviewed in this article suggest that circulating endogenous sex hormones and estrogens have a neutral or beneficial effect on cardiovascular disease in men. |
| doi_str_mv | 10.1210/jc.2003-030611 |
| format | Article |
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Vascular system</topic><topic>Cardiopathies: etiologic forms (general aspects and miscellaneous)</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - metabolism</topic><topic>Dehydroepiandrosterone - metabolism</topic><topic>Heart</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Risk Factors</topic><topic>Testosterone - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Muller, Majon</creatorcontrib><creatorcontrib>van der Schouw, Yvonne T.</creatorcontrib><creatorcontrib>Thijssen, Jos H. 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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Biological and medical sciences Cardiology. Vascular system Cardiopathies: etiologic forms (general aspects and miscellaneous) Cardiovascular Diseases - epidemiology Cardiovascular Diseases - metabolism Dehydroepiandrosterone - metabolism Heart Humans Male Medical sciences Risk Factors Testosterone - metabolism |
| title | Endogenous Sex Hormones and Cardiovascular Disease in Men |
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