Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries

Hyperhomocysteinemia is a significant risk factor in atherosclerosis and thrombosis. However, its role in the development of intimal hyperplasia after arterial reconstructive procedures remains uncertain. We therefore studied the effect of homocysteine on intimal hyperplasia in a rat model of caroti...

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Veröffentlicht in:	Atherosclerosis 2002, Vol.160 (1), p.103-114
Hauptverfasser:	Chen, Changyi, Surowiec, Scott M, Morsy, Amro H, Ma, Minhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Carotid Artery Injuries Catheterization - adverse effects Cell proliferation Disease Models, Animal Dose-Response Relationship, Drug Homocysteine Homocysteine - administration & dosage Homocysteine - blood Hyperplasia - drug therapy Hyperplasia - etiology Infusions, Parenteral Intimal hyperplasia Male Medical sciences Muscle, Smooth, Vascular - drug effects Rat Rats Rats, Sprague-Dawley Tunica Intima - pathology
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