Proline-Catalyzed Asymmetric Addition Reaction of 9-Tosyl-3,4-dihydro-β-carboline with Ketones

9-Tosyl-3,4-dihydro-β-carboline (1) reacted with a ketone in the presence of (S)-proline as a catalyst to give the corresponding addition product in good yield and high enantioselectivity. In the process, a small amount of water was found to affect the stereoselectivity of the products. The system w...

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Veröffentlicht in:	Organic letters 2003-11, Vol.5 (23), p.4301-4304
Hauptverfasser:	Itoh, Takashi, Yokoya, Masashi, Miyauchi, Keiko, Nagata, Kazuhiro, Ohsawa, Akio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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