Reduction in distractibility with AF102B and THA in the macaque

Distractibility in primates may be influenced by central cholinergic systems. Two cholinomimetics, the m-1 muscarinic agonist (±)- cis-2-methyl-spiro(1,3-oxathiolane-5,3′)quinuclidine (AF102B, civemeline) and the cholinesterase inhibitor tetrahydroaminoacridine (THA, tacrine), were compared to vehic...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2003-09, Vol.76 (2), p.301-306
Hauptverfasser:	O'Neill, Joseph, Siembieda, Douglas W., Crawford, K.Casey, Halgren, Eric, Fisher, Abraham, Fitten, L.Jaime
Format:	Artikel
Sprache:	eng
Schlagworte:	AF102B Animals Attention - drug effects Behavioral psychophysiology Biological and medical sciences Cholinergic system Cholinesterase inhibitors Cholinesterase Inhibitors - pharmacology Conditioning, Operant - drug effects Distractibility Female Fundamental and applied biological sciences. Psychology Macaca radiata Male Medical sciences Monkeys Muscarinic agonists Muscarinic Agonists - pharmacology Neuropharmacology Neurotransmission and behavior Neurotransmitters. Neurotransmission. Receptors Nootropic Agents - pharmacology Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychomotor Performance - drug effects Quinuclidines - pharmacology Space Perception - drug effects Tacrine - pharmacology THA Thiophenes Visual Perception - drug effects
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