Urinary excretion of retinol in patients with multiple myeloma: A preliminary study
Urinary excretion of vitamin A was studied in patients with multiple myeloma (MM). Eight of the 12 patients studied excreted retinol in urine; only one of them had elevated serum creatinine (115–150 μmol/L). There was a highly significant correlation between urinary retinol and serum creatinine (P &...
Gespeichert in:
| Veröffentlicht in: | American journal of hematology 2003-11, Vol.74 (3), p.202-204 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 204 |
|---|---|
| container_issue | 3 |
| container_start_page | 202 |
| container_title | American journal of hematology |
| container_volume | 74 |
| creator | Gavrilov, Vladimir Yermiahu, Tikva Gorodischer, Rafael |
| description | Urinary excretion of vitamin A was studied in patients with multiple myeloma (MM). Eight of the 12 patients studied excreted retinol in urine; only one of them had elevated serum creatinine (115–150 μmol/L). There was a highly significant correlation between urinary retinol and serum creatinine (P < 0.0004). Urinary retinol correlated also with urine protein (P < 0.0001) and albumin (P = 0.001), but not with urinary immunoglobulin light chains. Urinary retinol excretion may be an early manifestation of renal dysfunction in MM patients. The effect of urinary retinol excretion on vitamin A homeostasis in MM deserves further study. Am. J. Hematol. 74:202–204, 2003. © 2003 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/ajh.10407 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71326909</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71326909</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3867-44bce182b95230be2d01449033878dad29fd37ebda5fde3755dfac3f966de8da3</originalsourceid><addsrcrecordid>eNp10DtPwzAUBWALgaAUBv4A8gISQ-m1nSdbVQEFVWKAzpET36iunAd2opJ_T0oidWLyGT6dax1Cbhg8MgA-l7ttHzwIT8iEQRzMosDnp2QCImB9hviCXDq3A2DMi-CcXDDPj0Lw-YR8bqwupe0o_mQWG12VtMrpIZWVobqktWw0lo2je91sadGaRtcGadGhqQr5RBe0tmh0MbS4plXdFTnLpXF4Pb5Tsnl5_lquZuuP17flYj3LRBSEM89LM2QRT2OfC0iRK2CeF4MQURgpqXicKxFiqqSfKxSh76tcZiKPg0BhD8SU3A-9ta2-W3RNUmiXoTGyxKp1ScgED2KIe_gwwMxWzlnMk9rqov9vwiA5LJj0CyZ_C_b2dixt0wLVUY6T9eBuBNJl0uRWlpl2R-dzLwRxcPPB7bXB7v-LyeJ9NZz-BdH7iFQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71326909</pqid></control><display><type>article</type><title>Urinary excretion of retinol in patients with multiple myeloma: A preliminary study</title><source>Wiley Free Content</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Gavrilov, Vladimir ; Yermiahu, Tikva ; Gorodischer, Rafael</creator><creatorcontrib>Gavrilov, Vladimir ; Yermiahu, Tikva ; Gorodischer, Rafael</creatorcontrib><description>Urinary excretion of vitamin A was studied in patients with multiple myeloma (MM). Eight of the 12 patients studied excreted retinol in urine; only one of them had elevated serum creatinine (115–150 μmol/L). There was a highly significant correlation between urinary retinol and serum creatinine (P < 0.0004). Urinary retinol correlated also with urine protein (P < 0.0001) and albumin (P = 0.001), but not with urinary immunoglobulin light chains. Urinary retinol excretion may be an early manifestation of renal dysfunction in MM patients. The effect of urinary retinol excretion on vitamin A homeostasis in MM deserves further study. Am. J. Hematol. 74:202–204, 2003. © 2003 Wiley‐Liss, Inc.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.10407</identifier><identifier>PMID: 14587052</identifier><identifier>CODEN: AJHEDD</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Chromatography, High Pressure Liquid ; Creatinine - blood ; Creatinine - urine ; Fanconi Syndrome - etiology ; Fanconi Syndrome - urine ; Female ; Hemostasis ; Humans ; Immunodeficiencies. Immunoglobulinopathies ; Immunoglobulinopathies ; Immunopathology ; Male ; Medical sciences ; Middle Aged ; multiple myeloma ; Multiple Myeloma - complications ; Multiple Myeloma - urine ; proximal tubule dysfunction ; Renal Insufficiency - etiology ; Renal Insufficiency - urine ; Tropical medicine ; urinary retinol ; Vitamin A - metabolism ; Vitamin A - urine</subject><ispartof>American journal of hematology, 2003-11, Vol.74 (3), p.202-204</ispartof><rights>Copyright © 2003 Wiley‐Liss, Inc., A Wiley Company</rights><rights>2004 INIST-CNRS</rights><rights>Copyright 2003 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3867-44bce182b95230be2d01449033878dad29fd37ebda5fde3755dfac3f966de8da3</citedby><cites>FETCH-LOGICAL-c3867-44bce182b95230be2d01449033878dad29fd37ebda5fde3755dfac3f966de8da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.10407$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.10407$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,1427,27901,27902,45550,45551,46384,46808</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15247032$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14587052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gavrilov, Vladimir</creatorcontrib><creatorcontrib>Yermiahu, Tikva</creatorcontrib><creatorcontrib>Gorodischer, Rafael</creatorcontrib><title>Urinary excretion of retinol in patients with multiple myeloma: A preliminary study</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>Urinary excretion of vitamin A was studied in patients with multiple myeloma (MM). Eight of the 12 patients studied excreted retinol in urine; only one of them had elevated serum creatinine (115–150 μmol/L). There was a highly significant correlation between urinary retinol and serum creatinine (P < 0.0004). Urinary retinol correlated also with urine protein (P < 0.0001) and albumin (P = 0.001), but not with urinary immunoglobulin light chains. Urinary retinol excretion may be an early manifestation of renal dysfunction in MM patients. The effect of urinary retinol excretion on vitamin A homeostasis in MM deserves further study. Am. J. Hematol. 74:202–204, 2003. © 2003 Wiley‐Liss, Inc.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Creatinine - blood</subject><subject>Creatinine - urine</subject><subject>Fanconi Syndrome - etiology</subject><subject>Fanconi Syndrome - urine</subject><subject>Female</subject><subject>Hemostasis</subject><subject>Humans</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>multiple myeloma</subject><subject>Multiple Myeloma - complications</subject><subject>Multiple Myeloma - urine</subject><subject>proximal tubule dysfunction</subject><subject>Renal Insufficiency - etiology</subject><subject>Renal Insufficiency - urine</subject><subject>Tropical medicine</subject><subject>urinary retinol</subject><subject>Vitamin A - metabolism</subject><subject>Vitamin A - urine</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10DtPwzAUBWALgaAUBv4A8gISQ-m1nSdbVQEFVWKAzpET36iunAd2opJ_T0oidWLyGT6dax1Cbhg8MgA-l7ttHzwIT8iEQRzMosDnp2QCImB9hviCXDq3A2DMi-CcXDDPj0Lw-YR8bqwupe0o_mQWG12VtMrpIZWVobqktWw0lo2je91sadGaRtcGadGhqQr5RBe0tmh0MbS4plXdFTnLpXF4Pb5Tsnl5_lquZuuP17flYj3LRBSEM89LM2QRT2OfC0iRK2CeF4MQURgpqXicKxFiqqSfKxSh76tcZiKPg0BhD8SU3A-9ta2-W3RNUmiXoTGyxKp1ScgED2KIe_gwwMxWzlnMk9rqov9vwiA5LJj0CyZ_C_b2dixt0wLVUY6T9eBuBNJl0uRWlpl2R-dzLwRxcPPB7bXB7v-LyeJ9NZz-BdH7iFQ</recordid><startdate>200311</startdate><enddate>200311</enddate><creator>Gavrilov, Vladimir</creator><creator>Yermiahu, Tikva</creator><creator>Gorodischer, Rafael</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200311</creationdate><title>Urinary excretion of retinol in patients with multiple myeloma: A preliminary study</title><author>Gavrilov, Vladimir ; Yermiahu, Tikva ; Gorodischer, Rafael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3867-44bce182b95230be2d01449033878dad29fd37ebda5fde3755dfac3f966de8da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Creatinine - blood</topic><topic>Creatinine - urine</topic><topic>Fanconi Syndrome - etiology</topic><topic>Fanconi Syndrome - urine</topic><topic>Female</topic><topic>Hemostasis</topic><topic>Humans</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>multiple myeloma</topic><topic>Multiple Myeloma - complications</topic><topic>Multiple Myeloma - urine</topic><topic>proximal tubule dysfunction</topic><topic>Renal Insufficiency - etiology</topic><topic>Renal Insufficiency - urine</topic><topic>Tropical medicine</topic><topic>urinary retinol</topic><topic>Vitamin A - metabolism</topic><topic>Vitamin A - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gavrilov, Vladimir</creatorcontrib><creatorcontrib>Yermiahu, Tikva</creatorcontrib><creatorcontrib>Gorodischer, Rafael</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gavrilov, Vladimir</au><au>Yermiahu, Tikva</au><au>Gorodischer, Rafael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urinary excretion of retinol in patients with multiple myeloma: A preliminary study</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>2003-11</date><risdate>2003</risdate><volume>74</volume><issue>3</issue><spage>202</spage><epage>204</epage><pages>202-204</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><coden>AJHEDD</coden><abstract>Urinary excretion of vitamin A was studied in patients with multiple myeloma (MM). Eight of the 12 patients studied excreted retinol in urine; only one of them had elevated serum creatinine (115–150 μmol/L). There was a highly significant correlation between urinary retinol and serum creatinine (P < 0.0004). Urinary retinol correlated also with urine protein (P < 0.0001) and albumin (P = 0.001), but not with urinary immunoglobulin light chains. Urinary retinol excretion may be an early manifestation of renal dysfunction in MM patients. The effect of urinary retinol excretion on vitamin A homeostasis in MM deserves further study. Am. J. Hematol. 74:202–204, 2003. © 2003 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>14587052</pmid><doi>10.1002/ajh.10407</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0361-8609 |
| ispartof | American journal of hematology, 2003-11, Vol.74 (3), p.202-204 |
| issn | 0361-8609 1096-8652 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71326909 |
| source | Wiley Free Content; MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Aged Biological and medical sciences Chromatography, High Pressure Liquid Creatinine - blood Creatinine - urine Fanconi Syndrome - etiology Fanconi Syndrome - urine Female Hemostasis Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology Male Medical sciences Middle Aged multiple myeloma Multiple Myeloma - complications Multiple Myeloma - urine proximal tubule dysfunction Renal Insufficiency - etiology Renal Insufficiency - urine Tropical medicine urinary retinol Vitamin A - metabolism Vitamin A - urine |
| title | Urinary excretion of retinol in patients with multiple myeloma: A preliminary study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T16%3A36%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Urinary%20excretion%20of%20retinol%20in%20patients%20with%20multiple%20myeloma:%20A%20preliminary%20study&rft.jtitle=American%20journal%20of%20hematology&rft.au=Gavrilov,%20Vladimir&rft.date=2003-11&rft.volume=74&rft.issue=3&rft.spage=202&rft.epage=204&rft.pages=202-204&rft.issn=0361-8609&rft.eissn=1096-8652&rft.coden=AJHEDD&rft_id=info:doi/10.1002/ajh.10407&rft_dat=%3Cproquest_cross%3E71326909%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71326909&rft_id=info:pmid/14587052&rfr_iscdi=true |